A popular term for a HMG-CoA reductase inhibitor, which ↓ cholesterol–eg, pravastatin, lovastatin, etc, which ↓ progression of ASHD/CAD, even in absence of ↑ cholesterol. SeeAtorvastatin, Cervastatin,Fluvastatin,Lovastatin, Pravastatin,Simvastatin. ...
Higher cholesterol levels, not statin use, are associated with a lower risk of hepatocellular carcinoma Article Open access 20 December 2019 Statin use is associated with a reduced incidence of colorectal cancer expressing SMAD4 Article 26 October 2021 Statins and prostate cancer—hype or hope...
(Pharmacology) any of a class of drugs, including atorvastatin and simvastatin, that lower the levels of low-density lipoproteins in the blood by inhibiting the activity of an enzyme involved in the production of cholesterol in the liver
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People need a prescription to take statins, and most will take them for life once they start -- even if their LDL cholesterol levels go down. “I have had some patients that I can get off of a statin, but it tends to be one of those agents that we use lifelong,” Tracy said in ...
A synthetic statin is a type of competitive HMG-CoA reductase inhibitor used for lowering cholesterol levels. It is structurally different from natural statins and includes molecules like atorvastatin and rosuvastatin, which are highly effective in reducing LDL levels by more than 50%. ...
People need a prescription to take statins, and most will take them for life once they start—even if their LDLcholesterol levelsgo down. "I have had some patients that I can get off of a statin, but it tends to be one of those agents that we use lifelong," Dr. Tracy said in a ...
Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet. 2003;361(9364):...
The use of 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitor medications (‘statins’ or ‘HMG Co-A reductase inhibitors’) for cholesterol reduction has been hypothesised to interfere with cancer growth and metastasis through multiple mechanisms (Fenton et al, 1992; Herold et al, 1995; ...
Several studies have shown that statin, a cholesterol-lowering medication, reduces the risk of developing PD, but evidence for this is so far inconclusive. The objective of this study is to evaluate the association between statin use and the risk of developing PD. METHODS: PubMed, EMBASE, and...