No validated therapy for statin muscle pain exists. The goal of the study was to assess whether metformin was associated with reduced muscle pain. A secondary analysis of data from the ACCORD trial was performed
Sally, a 56 year old retired real estate agent, came to see me in the office with the chief complaint of hot flashes, night sweats, mood disturbance and weight gain which are all fairly typical post-menopausal symptoms. In addition, she also had leg pain for the past 3 months, which pr...
event; PREVENT III, Edifoligide for the Prevention of Infrainguinal Vein Graft Failure; REACH, Reduction of Atherothrombosis for Continued Health; RCT, randomized controlled trial; VQI, Vascular Quality Initiative; VSGNE, Vascular Study Group of New England; WALCS, Walking and Leg Circulation Study...
Side effects:The most common side effects of rosuvastatin (Crestor) are headache, depression, nausea, vomiting, stomach pain, indigestion, diarrhea, constipation, muscle aches or pains, joint pain, and sleep problems (insomnia or nightmares). The most serious side effects are liver failure, muscle...
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We present a case of a 46 year old patient, with a past medical history of deep vein thrombosis and hypercholesterolaemia, who was referred to hospital for investigation of a one day history of sudden onset of leg pain. The patient presented with unilateral calf tenderness and swelling that ...
After the dosage of cyclosporine was increased to 300 mg every day for 8 months, the patient developed body pain and leg weakness, with a serum creatine kinase increase and evidence on magnetic resonance imaging of muscle oedema.What is new and conclusionCyclosporine is a moderate inhibitor of ...
During this time, the patient developed leg fatigue while walking up stairs, diffuse muscle pain, and weakness. Statin-induced muscle toxicity was suspected. The creatine kinase level was elevated at 1263 U/L. The cardiologist stopped treatment with atorvastatin and prescribed coenzyme Q10.Krieger ...
Muscle pain (Brief Pain Inventory [BPI]), time to pain onset, arm and leg muscle strength, and maximal oxygen uptake (VO2max) were measured before and after each treatment. Results: Serum CoQ10 increased from 1.3 ± 0.4 to 5.2 ± 2.3 mcg/mL with simvastatin and CoQ10, but...