目标蛋白 SCG10/Stathmin-2 目标蛋白描述 Stathmin 2, Superior Cervical Ganglia, Neural Specific 10 (SCG10) 由基因 STMN2 编码,是 stathmin 家族磷蛋白的成员。Stathmin 2 参与调节微管动力学和信号转导。通过这种方式,Stathmin 2 在神经生长中发挥调节作用。Stathmin 2 在大脑神经元中表达,并存在于发育中的神...
The mRNA transcript of the human STMN2 gene, encoding for stathmin-2 protein (also called SCG10), is profoundly impacted by TAR DNA-binding protein 43 (TDP-43) loss of function. The latter is a hallmark of several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). Using...
1.一种包含人源化stathmin-2(stmn2)基因的小鼠,所述人源化stathmin-2(stmn2)基因包含外源多核苷酸序列,其中所述外源多核苷酸序列包含人stmn2外显子2a序列。 2.根据权利要求1所述的小鼠,其中所述人stmn2外显子2a序列的长度为约200-约300个核苷酸,任选地长度为约220-约225个核苷酸。 3.根据权利要求1或2所述...
Rabbit Polyclonal Stathmin-2/STMN2 Antibody 价格电议 起批量≥1 ml 最小起订电询 供货总量电询 发货地址上海市浦东新区 建议售价￥电议/ml 更新日期2025年01月23日 产品规格见优宁维官网 即时洽谈立即询价查看联系方式 收藏产品发送留言 VIP3年 上海优宁维生物科技股份有限公司A股...
Stathmin-2 (STMN2) is a microtubule-associated protein specifically expressed in neurons and required for axon outgrowth and maintenance, as well as for axon regeneration after injury in vitro. Loss or reduction of this protein in mice leads to progressive sensory and motor neuropathy resembling som...
The secretion of both glucagon and Stmn2 was significantly enhanced in response to 55 mM K+, and immunofluorescence confocal microscopy showed co-localization of stathmin-2 with glucagon and the secretory granule markers chromogranin A and VAMP-2 in ±TC1-6 cells. In mouse pancreatic islets, ...
CAS号: 英文名: Recombinant human Stathmin-2 protein 英文别名: Recombinant human Stathmin-2 protein 中文名: 重组 人STATHMIN-2 蛋白 中文别名: 重组 人STATHMIN-2 蛋白 CBNumber: CB613138486 分子式: 分子量: 0 MOL File: Mol file
产品名称: h/mStathmin-2 MAb (Cl 684433) (100 UG) .0 订购此产品 供应商: R&D 规格: 100UG 目录价: 3400 库存状态: CAS编号: 应用范围: 种属来源: 相关信息: 保存条件: 说明书地址: 点击查看详细 打印此页 关闭此页 上一个:hThemis MAb (Cl 701010) (100 UG)[MAB6929/100UG] 下一...
Stathmin-2 (STMN2), also known as superior cervical ganglion 10 protein (SCG10), is a 19 kDa microtubule-destabilizing protein that is preferentially expressed in neurons. It promotes neuronal proliferation and migration as well as neurite outgrowth. Stathmin-2 contains a membrane attachment region...
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