Number of times per week students must login to a typical course 7 Number of times per month faculty evaluate student participation 30 Number of times per month faculty provide feedback to students on participation 30 Courses requiring students to work collaboratively with other students Required in...
All authors read and approved the final version of the manuscript. Corresponding author Correspondence to Boris N. Kholodenko. Ethics declarations Competing interests A patent application (no. UK2107576.7) related to this work has been filed, with O.S.R., V.Z., W.K. and B.N.K. named ...
Targeting DMG via OXPHOS and cholesterol inhibition is a promising strategy in that the inhibitors of these pathways are clinically approved drugs and have been evaluated as chemo-sensitization agents in cancer clinical trials58,59. Moreover, a number of statins are known to penetrate the blood bra...
It is recognized that the tumor microenvironment (TME) plays a critical role in the biology of cancer. To better understand the role of immune cell components in CNS tumors, we applied a deconvolution approach to bulk DNA methylation array data in a larg
Furthermore, we linked the effect of VCX on EMT with the AhR levels by measuring the impact of VCX on AhR activity using IHC and IF in both in vivo and in vitro cells. As Fig. 7d illustrates, breast tissues isolated from Swiss albino mice treated with VCX (30 mg/kg) (IP) once a...
Cops Stop Ambulance On Way To Hospital And Fight With EMTCell phone video shows highway patrol grabbing paramedic by the throat http://www.youtube.com/watch?v=-wX5KMfjYYY&feature=haxa_popt00us09 Full story: http://www.infowars.net:80/articles/may2009/280509Fight.htm Take action online...
Further information and requests for resources and reagents should be directed to and will be fulfilled by the Lead Contact, Freda Miller (fredam@sickkids.ca). Experimental Model and Subject Details Mice All animal use was approved by the Hospital for Sick Children Animal Care Committee, in acco...
(basal) genes, but also showed high levels of luminal and mesenchymal gene expression (Fig.1k). We calculated the cumulativeZ-score mean of, as well as variance between, the luminal, myoepithelial, and epithelial–mesenchymal transition (EMT) genesets to serve as metrics of molecular ...
Even though the Krt8+ ADI gene programs resemble features found in EMT, we do not see conversion of epithelial cells to anything similar to fibroblasts. It seems that we rather see an overlap in gene expression patterns between cells undergoing genuine epithelial–mesenchymal transition (e.g. neur...