Over the past three decades, considerable efforts have been expended on understanding the Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway in leukemia, following the identification of the JAK2V617F mutation in myeloproliferative neoplasms (MPNs). The aim of thi...
Reviewed November 2022 Easy to use system On the whole a positive experience, nothing in life ticks all the boxes but adjustments can me made to suit your business found Statii customer support excellent PROS Having never used an ERP system I found it easy to use, eliminating repetitive entrie...
Registrations distribution on 27 November 2023, by countryCountry Registered domainsShare, % United States of America 113,088 36.09% Unknown 56,015 17.88% Iceland 31,503 10.05% China 27,045 8.63% Hidden 13,330 4.25% Japan 7,547 2.41% Canada 7,381 2.36% Cyprus 5,270 1.68% ...
25 contributions in the last year No contributions on September 24th.No contributions on October 1st.No contributions on October 8th.No contributions on October 15th.No contributions on October 22nd.No contributions on October 29th.No contributions on November 5th.No contributions on November 12th.No...
STAT: With Suzanne Clément, Normand D'Amour, Lou-Pascal Tremblay, Stéphane Rousseau. -STAT shares with us the daily life of the staff of St-Vincent Hospital in Montreal (Canada).
Renal tubulointerstitial fibrosis is the hallmark of various chronic kidney diseases. Symmetric dimethylarginine (SDMA) is an independent cardiovascular risk factor in patients with chronic kidney diseases, which is mostly excreted through renal tubules.
Acute myeloid leukemia in the medically unfit elderly patients JosephEdmund, ...KapilMeleveedu, inLeukemia Research, 2023 2.12.1Pracinostat plus azacitidine Histone deacetylasesare chromatin-modifying enzymes regulating methylation in promoter regions. Overexpression of enzymes can causeleukemogenesis.Pracino...
November 26, 2024 As expected from the nature of the NEP25 model, podocyte number as determined by WT1-positive cells in glomeruli was significantly lower in the mice treated with LMB2 (Fig 6A). day 28 for NEP25), significantly reduced glomerular COL1A2 mRNA accumulation and histological...
Mrinal M. Gounder, MD, of Memorial Sloan Kettering Cancer Center in New York, New York, delves into the data supporting the recent FDA approval of nirogacestat (Ogsiveo) for the treatment of adult patients with desmoid tumors. On November 27, 2023, theFDA granted this approval to niro...
Article Open access 19 May 2023 JAK-STAT signaling maintains homeostasis in T cells and macrophages Article Open access 24 April 2024 The JAK/STAT signaling pathway: from bench to clinic Article Open access 26 November 2021 References Darnell, J. E., Jr, Kerr, I. M. & Stark, G....