Start Codonsdoi:10.1002/047120918X.emb1467start codonsJ. F. AtkinsUniversity of Utah Salt Lake City UTR. F. GestelandJohn Wiley & Sons, Ltd
Start-gain mutations can introduce novel start codons and generate novel coding sequences that may affect the function of genes. In this study, we systematically investigated the novel start codons that were either polymorphic or fixed in the human genomes. 829 polymorphic start-gain SNVs were ide...
All analysed start codons meet these criteria in one of these positions (underlined characters). Strikingly, the OOF-AUG3 is the only sequence matching the consensus sequence in both positions. Hence, the OOF-AUGs might prevent usage of the downstream in-frame AUGs even in cases where the ...
Mutational analysis and subcellular localization indicate that the gene encoding HetN uses two methionine start codons (M1 and M119) to encode two protein forms: M1 is required for protein localization, while M119 is primarily responsible for inhibitory function. Finally, we demonstrate that patS and...
Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo 来自 Semantic Scholar 喜欢 0 阅读量: 42 作者:M Tholen,LE Hillebrand,S Tholen,O Sedelmeier,SJ Arnold,T Reinheckel 摘要: The lysosomal has been reported to cleave various functionally important cytosolic...
To evaluate the expression of intracellular CLU, we investigate two start codons found within the CLU gene. One has been previously suggested as a canonical start site for sCLU. The other we investigate as a non-canonical start site for intracellular CLU based off of post-transcriptional ...
Altered discrimination of start codons and initiator tRNAs by mutant initiation factor 3 来自 国家科技图书文献中心 喜欢 0 阅读量: 37 作者:M O'Connor,ST Gregory,UL Rajbhandary,AE Dahlberg 摘要: IF3 is essential for ensuring the fidelity of the initiation step of translation in bacterial cells....
During translation, the mRNA codons are used to code for different amino acids that are used to form a protein molecule. Some of the mRNA codons...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tough ...
Erratum to “A cytosine-rich region upstream of start codons serving as a signal for initiation of translation in Encephalitozoon cuniculi?” [Mol Biochem Parasitol 2005;140:69–73]Erratum to “A cytosine-rich region upstream of start codons serving as a signal for initiation of translation in...
The role of RNA editing in conservation of start codons in chloroplast genomes rice and maize were aligned with a view to studying the conservation of translational start and stop codons created by RNA editing of homologous genes. It... K Neckermann,P Zeltz,GL Igloi,... - 《Gene》 被引...