Staphylococcus aureus in Continuous Culture: A Tool for the Rational Design of Antibiotic Treatment Protocolsdoi:10.1371/journal.pone.0038866In vitro measures of the pharmacodynamics of antibiotics that account for the factors anticipated for bacteria in infected patients are central to the rational design...
By quantifying growth inhibition, early killing and longer-term population clearance by all pairs of 14 antibiotics, we find that clearance interactions are qualitatively different, often showing reciprocal suppression whereby the efficacy of the drug mixture is weaker than any of the individual drugs ...
Community-associated, methicillin-susceptible, and methicillin-resistant Staphylococcus aureus bone and joint infections in children: experience from India. Previously, the treatment of Staphylococcus aureus infections was less complex, as most of those isolated were susceptible to 尾-lactam antibiotics. In...
Beta-lactam antibiotics targeting PBP1 selectively enhance daptomycin activity against methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 57, 5005–5012 (2013). 21 Leski, T. A. & Tomasz, A. Role of penicillin-binding protein 2 (PBP2) in the antibiotic susceptibility and ...
Acquisition of resistance to neomycin, gentamicin, fusidic acid, or clindamycin has been observed in three strains of Staphylococcus aureus and data from three patients infected with these strains are presented in detail. Clindamycin resistance followed the expected pattern by appearing in a strain of ...
葡萄球菌(Staphylococcus)属于厚壁菌门,是一类革兰氏阳性球菌,因常呈葡萄串状聚集而得名。已经鉴定出大约89种葡萄球菌及亚种。金黄色葡萄球菌(Staphylococcus aureus)为该菌属的模式菌种。 葡萄球菌是兼性厌氧菌,但在有氧条件下生长更快、更丰富,金黄色葡萄球菌亚种和解糖葡萄球菌厌氧除外。
Prosthetic joint infections (PJI) are severe complications in Orthopedics, with Staphylococcus aureus and Staphylococcus epidermidis being the most commonl... D Molina-Manso,G Del Prado,A Ortiz-Pérez,... - 《Journal of Antibiotics》 被引量: 26发表: 2012年 Significance of Staphylococcus epidermidis...
Methicillin-resistant Staphylococcus aureus, MRSA bacterium also be referred to as multiply-resistant Staphylococcus aureus or oxacillin-resistant Staphylococcus aureus, ORSA, evolved the ability to survive treatment with beta-lactam antibiotics, including penicillin, methicillin, and cephalosporins. Common strai...
The Journal of Antibiotics63,492–498 (2010)Cite this article 2739Accesses 16Citations Metrics Abstract We describe a collection of antibiotic-activatedStaphylococcus aureuspromoter-luxreporter strains that can be used to discriminate among antibiotic classes on the basis of their light production response...
believe that our approach is more likely to be successful in a real-world application than the use of antibiotics, some of which we have found to be relatively ineffective against 24 h S. aureusbiofilms even at multiples of the minimal inhibitory concentration. Although a final determination...