There are 3 bone cell types, namely, osteocyte, osteoblast and osteoclast that facilitate the continuous growth and remodeling process. Answer and Explanation: Most people undergo stages of bone growth and deterioration at the same time, regardl...
We have established previously that rat bone tissue, as well as rat and human-derived bone cells in culture, show a sex-specific response to gonadal steroids in stimulation of the specific activity of the BB isozyme of creatine kinase (CK) and DNA synthesis. This response could be modified ...
Conventionally, this process is divided into four overlapping stages; inflammation, soft callus formation, hard callus formation and bone remodeling. Fibrillar proteins (collagens) are the most abundant component of the extracellular matrix (>90 %) and constitute the primary building material in soft ...
Changes in bone remodeling rate influence the degree of mineralization of bone which is a determinant of bone strength: therapeutic implications. Bone strength depends on the volume of bone matrix, the bone microarchitecture, and also on the level of bone tissue mineralization. In addition to the ...
Early-stage chondrocytes exhibited a glycolytic phenotype with increased expression of genes involved in metabolism and antioxidation, whereas late-stage chondrocytes exhibited ultrastructural changes involving mitochondrial damage and stress-associated chromatin remodeling. Using the chemical inhibitor BTB06584, ...
After about 8 to 10 weeks, your tooth’s extraction socket (the hole) will have substantially filled in with newly formed bone. (Around 2/3rds of the way.) At around 4 months, the socket will be completely filled in with new bone. It then takes on the order of another 2 to 4 mon...
Explain the continuous growth and remodeling of the mature bone. What are the main phases schistosomiasis? What are its clinical manifestations? 1. Explain how the amount of yolk in an egg affects cleavage and early development. Explain how the...
(GDF), bone morphogenetic protein (BMP) andTGF-β, have been reported to be involved in the regulation of the follicular developmental process and cellular communication within the follicle [15]. The hypothalamic-pituitary–gonadal (HPG) axis plays a crucial role in the development of the antral...
One of the most interesting findings is that most DETFs share one common characteristic: they have been associated with developmental processes involving mesodermal derivatives. Many of them have been shown to activate or inhibit processes leading to muscle, cartilage, or bone formation53,54,55. In...
[69], tissue inflammation or remodeling [70], and others. On the other hand, LPA receptors play a role in pathological conditions such as fibrosis, reproductive disorders, and bone metabolism, and cancer [67,71] The results of our study showed that the effect of LPA on uterine contractility...