First-line, potent androgen blockade for patients with newly diagnosed, advanced-stage, castration-sensitive prostate cancer is confirmed as an effective strategy by data from the STAMPEDE and LATITUDE trials. Herein, we highlight the benefits, discuss caveats and consider the clinical care implications...
CONCLUSIONS: In patients with Gleason sum 7 prostate cancer tertiary Gleason grade 5 is significantly associated with higher pT stage and biochemical recurrence. Larger studies are needed to assess the predictive value of tertiary grade compared to other established parameters in predicting the long-...
which produces fluid that mixes with sperm from the testicles to make semen. The prostate is located in front of the rectum, below the bladder and above the penis, and cancer in the gland has four major stages.
(1997). Stage at diagnosis of prostate cancer in Connecticut by poverty and race. Ethnicity and Disease, 7, 215-220.Polednak AP. Stage at diagnosis of prostate cancer in Connecticut by poverty and race. Ethn Dis... AP Polednak - 《Ethnicity & Disease》 被引量: 92发表: 1997年 Prostate...
Prostate cancerActive surveillanceExpectant managementInsignificant cancerOvertreatmentToday only a minority of low-risk patients join an active surveillance protocol... M Graefen,S Ahyai,R Heuer,... - 《Der Urologe》 被引量: 37发表: 2008年 Reevaluation of myoglobin for acute chest pain evaluation:...
On multivariate analysis Gleason score 4 + 3 = 7 (p = 0.03), number of positive cores (p = 0.002), maximum percent of cancer per core (p = 0.006) and preoperative serum prostate specific antigen (p = 0.03) all correlated with pathological stage. Gleason score 4 + 3 = 7 on biopsy ...
Overall daily growth (kp) was calculated as: kp = (ki/2) - (apoptosis/0.5), based on the time of prostate cancer to undergo mitosis and apoptosis per day. Using logistic regression analysis, pathologic stage did not correlate with cell proliferation, apoptosis, or overall daily growth. ...
Understanding how the QoL changes in relation with the selected treatment option can be important to the urologist and individual patient to have realistic expectations as well as to optimise treatment decisions for the prostate cancer patient when exist several alternatives. 展开 关键词: cancer stage...
Use of Transrectal Ultrasound to Stage Prostate Cancer-Reply Jonathan I. Epstein, MD; Patrick C. Walsh, MD; Marné Carmichael, BS; et al Charles B. Brendler, MD Author Affiliations JAMA. 1994;272(7):516-517. doi:10.1001/jama.1994.03520070034025 Full...
For low-risk prostate cancers, there has been a shift toward active surveillance in many patients. This involves closely monitoring the cancer through regular check-ups, blood tests, imaging tests, and periodic prostate biopsies. This approach is often chosen because in many cases of low-risk pro...