Small-cell lung cancer (SCLC) represents approximately 15% of lung cancer cases and has a poor prognosis; about two-thirds of patients present at an extensive-stage (ES) disease state, and the 5-year overall survival (OS) rate is limited to only 1–5% (refs.1,2). The addition of an...
or bone fracture; patients with granulating incisions healing by secondary intention with no evidence of fascial dehiscence or infection are eligible but require weekly wound examinations - Patients with known hypersensitivity to Chinese hamster cell products or other recombinant human or humanized antibodie...
Secondary end points were toxicity, progression-free survival and overall survival. The treatment regimen was based on a phase II study, which demonstrated activity of docetaxel and irinotecan in patients with recurrent ovarian cancer (Ma¨enpa¨a¨ et al, 1999). In this study, neutropenia was ...
Not surprisingly, psychiatric symptoms, disorders, and emotional distress are relatively common among cancer patients, in particular those with end-stage cancer ([1], also see [2]; see Fig.1), which is the terminal phase of cancer—including hospice and the latter part of palliative care [1,...
or dual placebo q4w for 4 cycles, followed by single placebo q4w) within 1 to 42 days of completing cCRT, stratified by stage and receipt of prophylactic brain irradiation. The primary endpoints are progression-free survival and overall survival. The secondary endpoints are overall survival and...
disorders [9], 31.1% suffer from hypertension, 16.7% suffer from diabetes [10, 11]; the prevalence of hip fractures secondary to osteoporosis is 169 per 10,000 women-years [12], of breast cancer is 27.4 per 100,000 woman-years, and of cervical cancer is 19.2 per 100,000 woman-years ...
9Seattle Cancer Care Alliance, Seattle, WA, USA; 10University of Colorado HSC, Aurora, CO, USA; 11Charite´ Universita¨tsmedizin Berlin, Berlin, Germany; 12Elbeklinikum Buxtehude, Buxtehude, Germany; 13Cancer Research UK Clinical Centre, Southampton, UK; 14Royal Free Hospital, London, UK; ...
MRD negative < 10−4; positive ≥ 10−4 detected CLL cells per leukocytes, according to MRD-flow cytometry. For MRD-results from bone marrow please refer to Supplementary Figs. 1 and 2. Full size image After 5 years from the last dose of study medication, 80.4% of Hi-FCR ...
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Body mass index (BMI) influences the prognosis of patients with non-small cell lung cancer (NSCLC), including both early-stage and late-stage NSCLC patients that are undergoing chemotherapies. However, earlier research on the relationship between BMI and survival in patients taking epidermal growth...