132P Stage IV non-small cell lung cancer in the elderly: Real-world datadoi:10.1016/S1556-0864(21)01974-2J.C. MonteiroC. Amorim CostaM. Rebordo PiresA.C. CaetanoF.R. SalgueiroI. DominguesA.R. Meira GarciaE. JesusN.A. Bonito...
The patients with T1-4, N0-3, Msite0-1 and adeno- or squamous carcinoma of stage IV NSCLC had a longer OS with local thoracic surgery in combination with chemotherapy or chemoradiation. Introduction Surgery plays an important role in the treatment of non–small-cell lung cancer (NSCLC) in...
Detection of circulating tumor cells as a prognostic factor in patients undergoing radical surgery for non-small-cell lung carcinoma: comparison of the efficacy of the Cell Search Assay (TM) and the isolation by size of epithelial tumor cell method. Int J Cancer. 2011;129(7):1651–60. ...
The characteristics of the patients are: 3 female, 9 male; 60 (49-73) yrs.; performance status 90; 5× squamous cell carcinoma, 7× adenocarcinoma. The response were: partial remission n = 6, no change n = 3, progressive disease n = 3. A transient neutropenia (WHO-grade ...
December 17, 2021 Association of Stage Shift and Population Mortality Among Patients With Non–Small Cell Lung Cancer Raja Flores, MD1; Parth Patel, BA1; Naomi Alpert, MS2; et al Bruce Pyenson, FSA, MAAA3,4; Emanuela Taioli, MD, PhD2 Author Affiliations Article Information JAMA Netw Open....
Non-small cell lung cancer (NSCLC) is the leading cause of cancer mortality worldwide1. Surgical resection is the treatment of choice for early stage NSCLC. Visceral pleural invasion (VPI) in NSCLC is known as a poor prognostic factor with worse survival and an important stage descriptor2,3....
Immune-Related Adverse Events Supplement 4. Data Sharing Statement 1. Borghaei H, Paz-Ares L, Horn L, et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N Engl J Med. 2015;373(17):1627-1639. doi:10.1056/NEJMoa1507643 PubMedGoogle...
activate the NF-κB pathway in non-small lung cancer, participate in mitogen-activated protein kinase (MAPK)/β-catenin signaling in nasopharyngeal cancer and regulate the PI3K, Rac, and Src signaling pathways in breast cancer48,49,50,51. The NF-κB signaling pathway is a classic signaling pa...
Thirty-five patients affected by stage III-IV non-small-cell lung carcinomas were treated with ifosfamide 3 gr/m2 plus MESNA as uroprotector on day 1 and vinorelbine 25 mg/m2 i.v. bolus on day 1 and 8. This cycle was repeated every 21 days. Over a total of 35 evaluable patients, ...
Bronchogenic carcinomaStage IASurgeryLymph node excisionMortalityTO determine the causes of death in patients treated surgically for nonsmall cell lung cancer (NSCLC) in stage IA and to evaluate the impact on survival of not performing systematic lymph node dissection and of the number of nodes ...