References 1. Angelov I, et al. Cardiovascular Disease and Breast Cancer Stage at Diagnosis. JAMA Netw Open 2025 Jan 2;8(1):e2452890. doi: 10.1001/jamanetworkopen.2024.52890 2. Agha A, et al. Long-Term Risk of Death From Heart Disease Among Breast Cancer Patients. Front....
46 Similarly, in breast cancer (BC) metastasis, the splicing factor SNRPA1 interacts with hundreds of structure-enhancing splicing enhancers enriched near cassette exons to promote cassette exon inclusion, enhancing BC cell invasion and lung colonization.47 Genetic alterations occurring at the gene level...
She is involved with numerous charities including Stand Up To Cancer and Revlon Run/Walk For Women raising awareness about breast cancer research funding. Furthermore, she has been vocal about mental health issues drawing upon personal experiences dealing with anxiety since childhood. Di...
APL-1202 is also being studied in two pivotal, phase 2/3 trials––in combination with intravesical chemotherapy for intermediate- and high-risk patients with non–muscle invasive bladder cancer (NMIBC) following relapse on chemotherapy, and ...
(DNAm) is an epigenetic marker placed on cytosine bases and is used to regulate gene expression and cell differentiation40; cell-type specific genes can be expressed and are hypomethylated, while other genes are repressed with hypermethylation of regulatory gene elements41. These durable, intrinsic...
Immunotherapies targeting the PD1/PD-L1 pathway have had a large impact on the treatment of advanced NSCLC. Concerning multimodality tumor therapy, only few trials until today have been performed investigating neoadjuvant treatment with anti PD-1 immunotherapy prior to curative intent surgery. Aim of ...
2.5. Treatment conditions 2.5.1. Behavioral Exposure For Interoceptive Tolerance (BE-FIT) BE-FIT is manualized intervention that involves six individually-tailored sessions (approximately 45–60 min each) delivered twice per week during the first three weeks of CR, as a supplement to CR. BE-FIT...
advanced-stage lung cancer;quality of life;functional status;individualized management 1. Background Lung cancer remains the leading cause of cancer-related death in the United States and makes up 12–13% of all cancer diagnoses, second to prostate cancer in men and breast cancer in women [1]...
Based on CPMV's efficacy as a therapy in early-stage established murine ovarian cancer, and its immunostimulatory properties, we use CPMV as an adjuvant to model treatment during patients' periods of remission. We propose to use the tumor as a remission- stage vaccine antigen source. By ...
She is involved with numerous charities including Stand Up To Cancer and Revlon Run/Walk For Women raising awareness about breast cancer research funding. Furthermore, she has been vocal about mental health issues drawing upon personal experiences dealing with anxiety since childhood. Als...