Summary Background and objectives The melanoma guideline is mainly based on the AJCC stage. There is no difference according to histological subtypes such as superficial spreading melanoma (SSM), lentigo maligna melanoma (LMM) or nodular malignant melanoma (NM). We aimed to evaluate whether ...
The primary treatment for early-stage melanoma is surgery, which is considered standard of care and provides excellent long-term prognosis. The goal of wider and deeper excision around the primary tumor site is to prevent local recurrence from persistent disease, by complete removal of the tumor ...
The good prognosis group (93% of patients surviving eight years) consisted of women with melanomas that were 1.5 mm thick or less. The intermediate prognosis group (78% of patients surviving eight years) consisted of men with nonulcerated melanomas that were 1.5 mm thick or less. The poor ...
BACKGROUNDCutaneous melanomas are aggressive tumors with an unpredictable biologic behavior. It has been suggested that women who present with melanoma during pregnancy have a worse prognosis due to more aggressive behavior of the melanoma. The objective of the current study was to evaluate the long...
90 Nevertheless, in melanoma cells, overexpression of the nerve growth factor receptor NGFR (CD271 / p75NTR) will downregulate NK cell activation ligands while upregulating fatty acid stearoyl coenzyme A dehydrogenase, which reduces NK cell infiltration, cell degranulation and the sensitivity of ...
Cutaneous melanoma, stage 1, from 35 survivors at 5 year follow-up and 16 non-survivors were studied. Mean nuclear area in the superficial layer was significantly larger than in the deep layer both in survivors and non-survivors, but the ratio between nuclear area in superficial and deep laye...
被引量: 0发表: 2018年 Mycosis fungoides Patients with stage IA-disease have an excellent prognosis with an overall long-term life expectancy that is similar to an age-, sex-, and race-matched control population. Almost all patients with stage IA MF will die from causes ... Z Pier Luigi...
In our series, regression was found in 16% of stage III melanoma patients. Histological regression has traditionally been considered as a marker of poor prognosis, mainly in thin melanomas, as it hampers a real evaluation of the initial thickness of the tumour. However, the majority of these ...
Occurrence of tertiary lymphoid tissue is associated with T-cell infiltration and predicts better prognosis in early-stage colorectal cancers. PURPOSE: Tumor-infiltrating T lymphocytes (TIL) play a key role in the clinical outcome of human colorectal cancer; however, the dynamics of their recruitm....
Detection of micrometastases in the regional tumor-draining lymph nodes is critical for accurate staging and prognosis in melanoma patients. We hypothesized that a multiple-mRNA marker (MM) reverse transcriptase-polymerase chain reaction (RT-PCR) assay would improve the detection of occult metastases ...