MUC1 goes through the process of autocleavage at a SEA (sperm protein, enterokinase and agrin) domain, and splits into MUC1 N-terminal (MUC1-N) and C-terminal (MUC1- C) subunits, which in turn form a non-covalent heterodimer [27, 28]. MUC1-N as a physical barrier protects normal...