A. Transcriptional Profile of Muscle following Acute Induction of Symptoms in a Mouse Model of Kennedy’s Disease/Spinobulbar Muscular Atrophy . PloS One 10 , e0118120, (2015).10.1371/journal.pone.0118120 [ Cross Ref ]Halievski, K.; Mo, K.; Westwood, J.T.; Monks, D.A. ...
The primary symptoms of Parkinson’s disease — tremors, muscle stiffness, slow movement, and impaired balance — can vary from person to person depending on what subtype of Parkinson’s they have, but they generally get worse over time. The three Parkinson’s subtypes are: (20) Akinetic-Rig...
In some patients, Parkinson’s causes other motor symptoms, including vision problems such as blurred vision or difficulty looking up, painful muscle cramps (dystonia), and difficulty maintaining an upright posture which can lead to stooping and abnormal curvature of the spine (scoliosis or kyphosis...
While the main symptoms of Parkinson's disease are movement-related, progressive loss of muscle control and continued damage to the brain can lead to secondary symptoms. These secondary symptoms vary in severity, and not everyone with Parkinson's will experience all of them, and may include: Anx...
Properties of cardiac muscles, Cardiac automaticity, and Conduction of electrical impulsesHistology of the heart, Cardiomyocyte types, Ultrastructure, and features of cardiac muscle fibersMediastinum contents, Aorta parts, Brachiocephalic trunk, Pulmonary trunk, and Thoracic duct trunk...
On the basis of a small series of autopsy studies, dysphagia probably depends on LTS pathology of the pharyngeal nerves and localized muscle atrophy10 and thus one would not expect to see an effect by DBS.10 However, some patients may also show abnormal esophageal peristaltic move- ments, ...
As the disease progresses, weakness or atrophy spread throughout the body. Patients may have trouble moving, swallowing and speaking. An ALS diagnosis requires signs of both upper and lower motor neuron damage. Signs of the former include muscle tightness or stiffness and abnormal reflexes; signs ...
Ever since it was first recognized,1 Parkinson's disease (PD) has been primarily identified by its cardinal motor symptoms: tremor, bradykinesia, muscle rigidity, and gait instability.2 Current therapies act mainly on the dopaminergic system,3 with the overall goal of improving motor symptoms and...
Enizimatic defects: glucose-6-phosphatase, liver phosphorylase ,pyruvate – carboxylase, glycogen synthase; deficit of substrates: ketosis hypoglycemia in children, malnutrition, muscle atrophy, advanced pregnancy. Liver disease:acute fulminant hepatitis, hepatic congestion,severe forms ...
HT is effective in vulvovaginal atrophy and may improve sexual function and other related symptoms such as joint and muscle pains, mood changes and sleep disturbances. However, prescriptions for HT have continued to tumble. Unfortunately, the WHI 2002 findings in older women with an intact uterus...