The Regulation on Amendments to the Regulation on Payment Services and Is... For more 2 April 2025 Amendments to the Communiqué on the Decision No. 32 on the Protection of... For more 28 March 2025 The Communiqué on Principles and Procedures Regarding Information System... ...
Liu H, Hu X, Zhu Y, Jiang G, Chen S. Up-regulation of SRPK1 in non-small cell lung cancer promotes the growth and migration of cancer cells. Tumor Biol. 2015;37:7287-93.Liu H, Hu X, Zhu Y, Jiang G, Chen S. Up-regula- tion of SRPK1 in non-small cell lung cancer promotes...
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(unpublished data). It was noted in our initial studies that cell lines expressing increased SRPK1 also appeared to express higher SRSF1 levels, which would support an additional level of regulation by the phosphorylating kinase. SRSF1 expression is essential, and depletion of SRSF1 has been ...
Immunoblotting showed that while there was a decrease in SRPK1 protein level in cisplatin-treated MCF7 cells, the kinase was upregulated by the drug in 231 cells (Fig. 1c; Supplementary Fig. 2). Interestingly, SRPK1 expression was not affected by the treatment in either MCF7R or 231R ...
Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle. Authors - Piazzon Nathalie N View Article human IHC Int J Oncol Significance of signal recognition particle 9 nuclear translocation: Implications for pancreatic cancer prognosis and functionality ...
Load regulation Regload los — 10 Output short current Temperature stability –30 — –100 –180 mA ∆Vref 80 — ppm/°C Io =–1 mA, 1 1 –20°C ≤ Ta ≤ 105°C Output noise voltage VN — 100 — µV 10 Hz ≤ fnoise ≤ 10 kHz Notes: 1. Referenc...
One of these pathways, regulation of aberrant protein production (RAPP), recognizes aberrant secretory proteins during translation and degrades the associated mRNA. Here, we demonstrate endogenous RAPP substrates. Haploinsufficiency of the secretory protein progranulin (GRN) is associated with the ...
In HeLa cells, both SRPKIN-1 and the less-selective reversible compound JH-VII-139-1 potently decreased the level of SR phosphorylation in a dose-dependent manner, leading to increased VEGF-A165b RNA as well as protein even at a dose of 200 nM. In comparison, the first-rgeneration SRP...
Homeostatic regulation of HSR thus requires a novel type of SRP recognition mechanism. The heat shock response (HSR) is a ubiquitous cellular strategy for coping with damaged proteins and maintain- ing homeostasis by ensuring appropriate expression levels of heat shock proteins (HSPs)1. Upon ...