关键 词: SREBP— l c启动子; FoxO1; 双荧光素酶报告基因分析 中图分类号 : R 34 文 献标 志码 : A C onstruction of p GL 3— -B asic--S R E B P --l c ·-promoter reporter gene v ector and detection of its function LIU X iao-jun, KONG X ing— xing,WANG Rui,SHAO Di,...
To investigate the effect of sterol regulatory element binding protein‐1c(SREBP1c)gene on lipid deposition in pigs,the longest dorsal muscle and subcutaneous adipose tissue at different fattening periods were collected from Huainan pigs in this study,and the expression trends of SREBP1c were ...
dise勰e;SREBP・1c;gene;sin舀e 硼clcotide polymorphism 3 s肛BP—lc基因单核苷酸多态性与非酒精性脂肪肝的关系 综述 自从1980年LudWig首次发现非酒精性脂肪肝(Nonalcoh01icfatty 1iver disease,NAFLD)以来,NAFLD已成为全球范围内普遍存在的具有流行病学的疾 ...
参考文献 Y in J,工脱MS,L艘HJ,“口z.Horrnonesandnutrients I rat [1]KirIl regulateacetyl—COAcarboxyIasepromoter prirllaryhepatoc”es..,D“r撇Z s S b is sterol el咖ent- [2]OhY,ParkK,KimJw,甜口z.Acetyl-coAcarboxylasegeneregulatedby regulatory inliver..,伽r懈Z bindingproteiIrl o,Bio...
Syngene公司 Heraeus公司 BectonDickinson公司 细胞培养与实验分组:将大鼠胰岛素瘤INS.1细胞于含10%FBS的RPMll640 完全培养基(1O%太牛血清,葡萄糖11.2mmol/1,lOmmol/l Hepes,lmmol/l丙酮 酸钠,50umol/L13巯基乙醇,lOOu/ml青霉素和100u∥ml链霉素)中37。C,5%C02 条件下培养,隔天换液1次,7天传代1次,取对数...
膀胱平滑肌细胞Many types of cells包装:5 × 105次方(1ml)卫矛醇半固体琼脂100毫升2~8℃CLIAKitforTIEG1(HumanTGF-beta-inducibleearlyresponsegene-1)ELISAKit人TGF-β诱导早期基因1规格:48T/96T 膀胱平滑肌细胞Many types of cells包装:5 × 105次方(1ml)色氨酸肉汤250毫升2~8℃,避光CLIAKitforTIEG1ELISAKit...
To evaluate the expression and the correlations of liver X receptor (LXR) and its target gene sterol regulatory element-binding protein-1c(SREBP-1c) in placenta and serum during the course of pre-eclampsia (PE) and their relationship in PE. 2. To evaluate the correlations between...
贞清方调节SREBP 1C减少糖尿病大鼠肾脏脂质沉积
11. After insulin treatment, FOXO1 protein is phosphorylated by AKT and then moves to the cytoplasm, resulting in the decrease of gluconeogenic gene expression12. Although the translocation of hepatic FOXO1 from the nucleus to the cytoplasm is a well-defined mechanism mediating a quick decrease in...
High glucose induced lipid synthesis leads to β cell glucolipotoxicity. Sterol regulatory element binding protein-1c (SREBP-1c) is reported to be partially involved in this process. Insulin induced gene-1 (Insig-1) is an important upstream regulator of Insig-1-SREBPs cleavage activating protein...