Src Homology 2 (SH2)结构域是介导信号分子与含哪种氨基酸的蛋白分子结合?A.磷酸苏氨酸B.磷酸丝氨酸C.脯氨酸D.磷酸酪氨酸
Molecular recognition and biochemical selectivity exists for various SH2 domains based on their binding to phosphotyrosine (pTyr) and contiguous C-terminal amino acids of cognate protein ‘partners’ in a sequencedependent manner (i.e., ∼pTyr-AA1-AA2-AA3∼) which result in the formation ...
SH2功能域(Src homology 2,SH2) 相关知识点: 试题来源: 解析 SH2功能域(Src homology 2,SH2) 细胞内内信号转导分子所具有的一个高度保守而无催化活性的、可与磷酸化酪氨酸结合的Src同源区。主要介导蛋白质之间的相互作用,参与形成信号复合体和组成信号转导链。
Anti-SHP2/PTPN11(Src homology 2 (SH2) domain containing phosphotyrosinephosphatase 2)??蛋白酪氨酸磷酸酶2抗体 抗原常规性能介绍 注意事项:本产品在存放时切记,不得长时间暴露在空气中,否则会降低本产品的含量,影响您的实验结果 产品说明:抗体即为免疫球蛋白,是改变了的球蛋白分子。由特抗原刺激产生,抗体...
SH2结构域 (Src homology 2 domain) 相关知识点: 试题来源: 解析 与原癌基因src编码的酪氨酸蛋白激酶区同源的结构域,能识别和结合蛋白分子中磷酸 化的酪氨酸及其相邻的3-6个氨基酸残基所构成的基序,即SH2结合位点。具有SH2结合位点的蛋白质与具有SH2结构域的蛋白质可以相结合。
Src homology 2 (SH2)-containing inositol 5 -phosphatase (SHIP) is an enzyme that catalyzes the dephosphorylation of phosphatidylinositol (3,4,5) triphosphates [PtdIns(3,4,5)P 3 ] and generates phosphatidylinositol (3, 4) diphosphates [PtdIns(3,4)P 2 ] (17, 18). Because various kinds ...
Src Homology 2 (SH2)结构域是介导信号分子与含哪种氨基酸的蛋白分子结合?A.磷酸苏氨酸B.磷酸丝氨酸C.脯氨酸D.磷酸酪氨酸的答案是什么.用刷刷题APP,拍照搜索答疑.刷刷题(shuashuati.com)是专业的大学职业搜题找答案,刷题练习的工具.一键将文档转化为在线题库手机刷题,以提
2.名词解释细胞通讯(cellcommunication) 参考答案: 在多细胞生物的细胞社会中,细胞间或细胞内高度精确和高效地发送与接受信息的通讯机制,并通过放大机制引起快速的细胞生理反应。 3.名词解释G蛋白耦联受体(G-proteincoupledreceptor) 参考答案:一种与三聚体G蛋白耦联的细胞表面受体。含有7个穿膜区,是迄今发现的最大...
interact with EGFR following ET-1 treatment. In SHP-2 knockdown NRK-52E cells, ET-1-induced EGFR transactivation was dramatically elevated and not influenced by NAC. However, GM6001 (an MMP inhibitor) and heparin binding (HB)-EGF neutralizing antibody suppressed this elevation. Our data suggest...
SH2 domains have been shown to enable the interaction of these signaling proteins with growth factor receptors such as FGFR1, EGFR, c-Met, and PDGFR in a phosphospecific manner (4., 5., 6., 7., 8., 9.). Subsequently, random peptide library screening approaches were used to define ...