The src family of tyrosine kinases (srcFK) are important upstream regulators of Rho-kinase mediated Ca-sensitization and constriction in rat pulmonary artery (RPA). We hypothesise that srcFK act through modulation of the activity of RhoA. Cytosolic to membrane translocation of RhoA in RPA smooth ...
The Src family of tyrosine kinases is important for embryonic stem cell self-renewal J. Biol. Chem., 279 (2004), pp. 31590-31598 Boggon and Eck, 2004 T.J. Boggon, M.J. Eck Structure and regulation of Src family kinases Crossref ...
SFK, Src-family kinase; TK, tyrosine kinase. The modular structure of Src-kinases comprises a short N-terminal segment where a myristoylation (or more rarely palmitoylation) site occurs, which is sequentially followed by the so-called Unique domain, an SH3 domain, an SH2 domain, and the TK...
4. Boggon T J , Eck M J . Structure and regulation of Srcfamily kinases[J]. Oncogene.5.Roskoski, Robert.Src protein-tyrosine kinase structure, mechanism, and small moleculeinhibitors[J]. Pharmacological Research, 2015, 94:9-25.6.Aleshin, A, Finn, etal. SRC: a century of science ...
3. https://en.wikipedia.org/wiki/Oncogene 4. Boggon T J , Eck M J . Structure and regulation of Srcfamily kinases[J]. Oncogene. 5.Roskoski, Robert.Src protein-tyrosine kinase structure, mechanism, and small moleculeinhibitors[J]. Pharmacological Research, 2015, 94:9-25. 6.Aleshin, A...
Src family kinases, key regulators of signal transduction. Oncogene. 2004;23(48):7906-7909. 2.Roskoski R. Src protein-tyrosine kinase structure, mechanism, and small molecule inhibitors. Pharmacol Res. 2015;94:9-25. 3.Frame MC. Src in cancer: deregulation and consequences for cell behaviour...
Furthermore, in vitro studies suggest that the Src family of tyrosine kinases critically regulates glutamatergic cellular functions within the DH. Thus, Src-family kinases in the DH may similarly control contextual cocaine- seeking behavior. To test this hypothesis, rats were trained to lever press ...
Na,K-ATPase activity in lens epithelium is subject to control by Src family tyrosine kinases (SFKs). Previously we showed hyposmotic solution causes an SFK-dependent increase in Na,K-ATPase activity in the epithelium. Here we explored the role of cAMP in the signaling mechanism responsible for...
英文名称 RatScrFamilyTyrosineProteinKinases(SrcPTKs)ELISAKit 检测指标缩写 SrcPTKs 可检测指标 凝集蛋白家族10(Colletin-10) 检测种属 植物 应用 定性检测 快递 顺丰包邮 检测限 详见说明书 货期 现货 品牌 佰利莱 价格说明 价格:商品在爱采购的展示标价,具体的成交价格可能因商品参加活动等情况发生变化...
of unicellular Src has provided novel insight into the evolution of Src biochemical regulation in multicellular organisms (see below). In mammals, Src, Fyn, and Yes (SYF) are ubiquitously expressed, while the other family members display more restricted expression profiles. As tyrosine kinases, SFK...