squamous epitheliumparakeratosisorhyperkeratosis. As cytologic sampling only obtains cells from the top two to three layers, a cytologic sample from a woman of child-bearing age should show the presence of only superficial and intermediatesquamous cells(Fig. 21.1). Superficial cells show abundant polyg...
Abnormalities of differentiation and maturation in the oesophageal squamous epithelium of patients with tylosis: Morphological features. Histopathology 1991;19:303.Ashworth MT, Nash JR, Ellis A, et al. Abnormalities of differentiation and maturation in the oesophageal squamous epithelium of pa- tients ...
Reactive Anal Transitional Zone Epithelium The ATZ epithelium is unique to the anal canal and raises diagnostic issues similar to those of immature squamousmetaplasiagiven its stratified appearance without significant squamous epithelial maturation. A useful diagnostic tool to distinguish reactive ATZ fro...
AbramovichCM,WasmanJK,SiekkinenP,Abdul-KarimFW.Histopathologic correlation of atypical parakeratosis diagnosed on cervicovaginal cytology.Acta Cytol. 2003;47:405-9. [Google Scholar] ShermanME,SchiffmanMH,LorinczAT,ManosMM,ScottDR,KurmanRJ, et al.Toward objective quality assurance in cervical cytopatholog...
A, Tissue section of the junction of the ectocervical (or mature metaplastic) epithelium with the endocervical mucosa. The arrow highlights the SCJ. B, Immunofluorescence for cytokeratin 7 (CK7) of a comparable region in another cervix demonstrates intense staining of a cuboidal cell population at...
Parakeratosis A disturbance of keratinization characterized by the retention of nuclei in the stratum corneum. Photodamage Skin changes consequent to exposure to the sun’s ultraviolet radiation. Positron emission tomography (PET) A nuclear medicine, functional imaging technique that is used to observe me...
One observes pronounced orthohyperkeratosis with focal parakeratosis, hypergranulosis, and irregular acanthosis (99). In addition, there may be papillomatosis and irregular downward proliferation of the epidermis and adnexal epithelium (100) approaching pseudoepitheliomatous hyperplasia (101) (Fig. 7-6)...
Initial gross changes are foci of leukoplakia followed shortly by irregular thickening of the epithelium, particularly the basal layer, along with a mixture of hyperkeratosis and parakeratosis. As tumors first begin to appear within 6鈥 10 weeks after initiation of carcinogen exposure, their shape ...
All cases were stained with hematoxylin and eosin (H&E) and reviewed. Cases in which the epidermis overlying nevi featured atypical appearing basal keratinocytes in otherwise fully differentiated epithelium, variable degrees of acanthosis and parakeratosis were selected for additional investigation.Thirty ...
In a retrospective study of 28 women and eight men with squamous cell metaplasia in different parts of the bladder, including the trigone, no histopathological differences were observed among the regions. All the five (female) patients with parakeratosis had a concomitant invasive bladder tumour. ...