Smoking and consuming alcohol leads to dangerous disease Squamous cell Lung Cancer (SqCLC). It is widespread all over the world today. The mortality rate of this cancer is on the higher side as it is diagnosed in stage III or IV. Small nodules are formed in the lungs in the starting ...
Squamous cell carcinoma of the lung, also known as squamous cell lung cancer, is a type of nonsmall cell lung cancer (NSCLC). Squamous cell lung tumors often occur in the central part of the lung or the main airway, such as the left or right bronchus. The principal causative agent of ...
Gene-expression-profiling studies have been undertaken in an attempt to identify the cell-of-origin for a variety of malignancies, including lung cancer, by comparing expression profiles of cancer cells to those obtained from sorted cell populations or cell lines obtained from non-neoplastic lung tis...
170,171In the early stages of OSCC, CCND1 is upregulated and contributes to the proliferation of OSCC cells.172Particularly, CCND1 is more likely cytoplasmically expressed in advanced OSCC with deleterious differentiation, increased mitosis, and invasive cell morphology.173Elevated expression of CCND1...
Stages of squamous cell carcinoma Your test results will help your doctor understand how far cancer cells have spread in your body and which stage the cancer is in. That way, they can find the best treatment for you. Stage 0 squamous cell carcinoma:This is the earliest stage of SCC. Canc...
Esophageal squamous cell carcinoma (ESCC) Being a very deadly disease, ESCC is the sixth leading cause of cancer deaths around the world with very low survival rate (Sung et al., 2021). OA has shown to promote apoptosis of TE13 and ECA109 ESCC cell lines by inducing G2/M phase ar...
The in vivo studies revealed that flavonoids alter the carcinogenesis by affecting the stages involved in cell proliferation such as initiation, promotion, and progression (Alam et al., 2018; Lambert and Elias, 2010). In the clinical trial, many flavonoids inhibited the proliferation of cancer ...
Lung squamous cell carcinoma (LUSC) is the second most common lung cancer worldwide, leading to millions of deaths annually. Although immunotherapy has expanded the therapeutic choices for LUSC and achieved considerable efficacy in a subset of patients,
Worldwide, lung cancer remains the deadliest malignancy which includes lung adenocarcinoma cancer (LUAD), lung squamous cell carcinoma (LUSC), large cell carcinoma (LCC), and small cell lung cancer (SCLC). LUSC is the second-largest subtype of non-small cell lung cancer. Due to the lack of...
Lung squamous cell carcinoma (SQCC) accounts for about 30% of all lung cancer cases. Understanding of mutational landscape for this subtype of lung cancer in Chinese patients is currently limited. We performed whole exome sequencing in samples from 100 p