Empty Cell Strength of consensus: 100%. AJCC, American joint committee on cancer; BWH, Brigham and women’s hospital; cSCC, cutaneous squamous cell carcinoma; GPP, good clinical practice point. * Specification of high-risk factors for imaging for non-palpable regional nodal metastasis cannot be ...
Esophageal squamous cell carcinoma (ESCC) is the sixth most common cause of cancer-related mortality worldwide, with more than half of them occurred in China. Radiotherapy (RT) has been widely used for treating ESCC. However, radiation-induced DNA damage
Is assessment of platelet-lymphocyte ratio and neutrophil-lymphocyte ratio a predictor for lymph node metastasis in oral squamous cell carcinoma? Systemic inflammation promotes tumorigenesis and metastasis in cancer. It has a role in the initiation and progression of oral cancer to advanced stages. P....
KLK8, one of the members of the KLKs family, is a synaptic, plasticity-modulating extracellular serine protease, involved with several malignant diseases, including ovarian cancer [11,12], cervical cancer [13], breast cancer [14], colorectal cancer [15,16], oropharyngeal cancer [17], gastric ...
Numerous studies have suggested that epithelial transitional zones (TZs, aka, epithelial junctions) are more predisposed to cancer than other regions in the same organ9,10,11,12,13. During recent years, it has been recognized that many TZs contain stem cell niches responsible for the tissue rege...
| DOI: 10.1038/ncomms12601 that cuSCC is most similar to HNSCC, followed by LUSC, basal (triple-negative) and HER2 breast cancer and ESCA SCC, but not closely related to cervical SCC, which is overwhelmingly human papillomavirus (HPV) -driven (Fig. 8a and Supplementary Data 10). This...
The mutation rate of the TP53 gene in human tumour cells has increased significantly from 10% (hae- matopoietic stem cell malignant tumour) to 50–70% (ovarian, colorectal, and head and neck cancer) [120]. Once the TP53 gene is mutated, the tumour suppres- sion function of the wild-...
Head and neck cancer is a malignant tumour with a high mortality rate characterized by late diagnosis, high recurrence and metastasis rates, and poor prognosis. Head and neck squamous cell carcinoma (HNSCC) is the most common type of head and neck cancer
Cancer family Weight loss Present 52 58.4 Absent 77 86.5 Absent 37 41.6 Present 12 13.5 ECOG Anatomical site Good 65 73.0 Anterior 40 44.9 Poor 24 27.0 Posterior 49 55.1 Tumour size Cervical metastasis T1/T2 34 38.2 Absent 44 49.4 T3/T4 55 61.8 Present 45 50.6 Overall survival WHO grade ...
ESOPHAGEAL AND GASTRIC CANCER LBA244 Oral Abstract Session Chemotherapy plus camrelizumab versus chemotherapy alone as neoadjuvant treatment for resectable esophageal squamous cell carcinoma (ESCORT-NEO): A multi-center, randomized phase III trial. Yin Li, Jianjun Qin, Liyan Xue, Anlin Hao, Tao ...