squamous cell carcinomasurgeryDifferentiation between lung squamous cell carcinoma and pulmonary metastasis of head and neck squamous cell carcinoma is clinically important because the prognoses and therapeutic options are considerably different. However, the clinical, pathological, and immunohistochemical ...
Squamous cell carcinoma (SCC) and adenocarcinoma (AC) are two main histological subtypes of solid cancer; however, SCCs are derived from different organs with similar morphologies, and it is challenging to distinguish the origin of metastatic SCCs. Here we report a deep proteomic analysis of 333 ...
In conclusion, high expression of IKKα may serve as an intracellular signal to halt the epithelial differentiation of SCC cells. Introduction Squamous cell carcinomas (SCCs) show various clinical and histological features according to their epithelial differentiation stage. Generally, poorly-differentiated...
Squamous cell carcinoma (SCC) is a malignant tumor showing evidence of squamous differentiation, e.g., intercellular bridges and/or keratinization. It arises from squamous epithelium or from respiratory epithelium that has undergone squamous metaplasia. Burden SCC is the most common malig...
Lung squamous cell carcinoma is a common type of lung cancer, causing approximately 400,000 deaths per year worldwide. Genomic alterations in squamous cell lung cancers have not been comprehensively characterized, and no molecularly targeted agents have been specifically developed for its treatment. As...
The head and neck/oral squamous cell carcinoma (HNOSCC) is a diverse group of cancers, which develop from many different anatomic sites and are associated with different risk factors and genetic characteristics. The oral tongue squamous cell carcinoma (O
Squamous cell carcinoma of the lung, also known as squamous cell lung cancer, is a type of nonsmall cell lung cancer (NSCLC). Squamous cell lung tumors often occur in the central part of the lung or the main airway, such as the left or right bronchus. The principal causative agent of...
CDX2 Is a Useful Marker of Intestinal-Type Differentiation: A Tissue Microarray-Based Study of 629 Tumors From Various Sites. Hepatocellular, poorly differentiated neuroendocrine carcinoma of the lung and squamous cell carcinomas of the lung were not immunoreactive for CDX2. ... De,Lott,Lindsey,....
摘要: Cancer Immunology, Immunotherapy - Myeloid-derived suppressor cells (MDSCs) are one of the tumor-infiltrating immune cell population, which play a powerful role in inhibiting anti-tumor immune...关键词: Adenosine Monocytes Myeloid-derived suppressor cells Oral squamous cell carcinoma STAT3 ...
Immune checkpoint blockade (ICB) approaches have changed the therapeutic landscape for many tumor types. However, half of cutaneous squamous cell carcinoma (cSCC) patients remain unresponsive or develop resistance. Here, we show that, during cSCC progres