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Bispecific antibodies are a successful and expanding therapeutic class. Standard approaches to generate bispecifics are complicated by the need for disulfide reduction/oxidation or specialized formats. Here we present SpyMask, a modular approach to bispe
Testis-specific protein,Y-encoded-like 2(TSPYL2) is an X-linked gene in the locus for several neurodevelopmental disorders. We have previously shown thatTspyl2knockout mice had impaired learning and sensorimotor gating, and TSPYL2 facilitates the expression ofGrin2aandGrin2bthrough interaction with...
The testing has concluded and my initial test of the Zebra AIT1 is complete. Thank you to Zebra and the MGS team for the opportunity to test the AIT1, this was a lot of fun and a great excuse to play A LOT of golf. This road was a little bumpy at times, but all and all a ...
Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators. Mol Cell Biol. 2000;20:8933–43. Article CAS Google Scholar Koos B, et al. Analysis of protein interactions in situ by proximity ligation assays. Curr Top Microbiol Immunol. 2014;377:111...
Certainly love being able to include the family in golf! And yes love being able to represent the lefty's. I've been known to seek out other southpaw's at courses when I see them playing. I just come over introduce myself and say hi. Sometimes I get goofy looks, which is ok. I ...
specified in this publication, we identified the candidates for all microRNAs belonging to that family. Those candidates that overlapped the experimentally derived sites were retained as positive instances. In cases where several candidates of the same microRNA family overlapped, we took the energetically...
TSPY contains a SET/NAP domain that is present in a family of cyclin B and/or histone binding proteins represented by the oncoprotein SET and the nucleosome assembly protein 1 (NAP1), involved in cell cycle regulation and replication. Methods To determine a possible cellular function for TSPY...
'Familiarity' refers to any comments given based on experience with actual tablets, either taken themselves or by family members. Of the comments g1i1v%en to the DLP printlets, appearance, taste and texture received higher proportions of positive coDmL Pments over negSaL Stive ones, unlikSeS...