YT / BVT Family? a. Hand Keyed variant M54- V89T,only null message format known M55 F x 6, 000 000,long zero, null message M56 1fig:5fig, long zero M57- UNDER RE-EVALUATION M58 ===3lt UNDER RE-EVALUATION M63 A2A M64- "= 3F 3F = 11111 5F, AR" M65- Ends "= = QRU QR...
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For the dsDNA target-bound SpyCas9-sgRNA ternary complex, displacement of the PAM duplex or melting of the guide:target heteroduplex requires overcoming a high energy barrier. In addition, domain rearrangement during pre-target-bound to target-dsDNA-bound generates a narrow surface for optimal ...