The major lymphatic pathway involved in the spreading of prostate cancer appears to relate to internal iliac LNs, which would mean that the standard PLND covering external iliac and obturator regions would not keep the cancer from spreading.
Cancer57 (l0): 2057, 1986 Article PubMed CAS Google Scholar Emmerova M, Malkusova I, Barcal R: Implantation of skin 37. metastases due to pericardial puncture. Vnitr Lek32 (3): 286, 1986 PubMed CAS Google Scholar Emtage JB, Perez-Marrero R: Extension of carcinoma of prostate along...
When prostate cancer stem cells (CSCs) were enclosed in self-assembling nanomaterials made of peptides (SAP), the SAP stopped cancer stem cell colony formation and also stopped the division of cancer cells in laboratory cultures (in vitro). According to the international team of researchers who ...
Exportin 1 (XPO1), also called chromosome region maintenance 1 (CRM1), is the sole exportin mediating transport of many multiple tumor suppressor proteins out of the nucleus. To verify the hypothesis that XPO1 inhibition affects prostate cancer (PCa) met
Planet Cancer: The Frequently Bizarre Yet Always Informative Experiences and Thoughts of Your Fellow Natives From Our Archives: Advance Directive From Our Archives: Art & Healing Teenage Tan Bans Spreading Across States Prostate Cancer Prevention Drugs Get a “No” Vote The Health Care Law: Rhetoric...
(which are also part of our genome!!!) is often overlooked despite the fact that, “increased HERV activityis largely associated with malignancy, especially cancer”. For instance, “Expression from HERV-K…. is upregulated in up to 85% of breast cancer samples, although the mechanism of ...
F. et al. The genomic complexity of primary human prostate cancer. Nature 470, 214–220 (2011). CAS PubMed PubMed Central Google Scholar Cibulskis, K. et al. ContEst: estimating cross-contamination of human samples in next-generation sequencing data. Bioinformatics 27, 2601–2602 (2011)....
Developing an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinic. Prostate cancer is the second leading cause of cancer-related deaths in men in the U.S. At present, no single or combination therapy has shown efficacy in ...
Lymphatic metastases are closely associated with tumor relapse and reduced survival in colorectal cancer (CRC). How tumor cells disseminate within the lymphatic network remains largely unknown. Here, we analyze the subclonal structure of 94 tumor samples
Protein systems, such as Ras, make up the complex signaling pathways that control whether a cell divides or, in some cases, becomes cancerous and metastasizes into other regions of the body. For example, 98 percent of pancreatic cancers show Ras protein