Acceptor splice siteNAGNAG motifTandem acceptor splice sitePre-mRNA splicing is an essential step in gene expression, when introns are removed and exons joined by the complex of proteins called spliceosome. Correct splicing requires a precise exon/intron junction definition, which is determined by a...
Significant association was detected at multiple markers, the strongest being at an A/G single-nucleotide polymorphism at the exon 7 splice-acceptor site (AG or AA) of the OAS1 gene. At this unusual polymorphism, allele G had a higher gene frequency in persons with high enzyme activity than...
Alternative splicing in the human cytochrome P450IIB6 gene: Use of a cryptic exon within intron 3 and splice acceptor site within exon 4. Nucleic Acids Res . 18 , 189.Miles JS, McLaren AW, Gonzalez FJ, Wolf CR (1990a) Alternative splicing in the human cytochrome...
了解“ splice acceptor site”的定义。检查一下发音,同义词和语法。浏览出色的英文语料库中的使用示例“ splice acceptor site”。
Intron splice acceptor site polymorphism in the hMSH2 gene in sporadic and familial colorectal cancer. Br J Cancer 2000, 82: 535- 537.Palicio M, Blanco I, Tortola S, Gonzalez I, Marcuello E, Brunet J, et al. Intron splice acceptor site polymorphism in the hMSH2 gene in sporadic and ...
( 1997 ) G to C transversion at a splice acceptor site causes exon skipping in the cystatin B gene . Mutat. Res. 382 , 67 – 74 ... Irina,N,Bespalova,... - 《Mutation Research/mutation Research Genomics》 被引量: 35发表: 1997年 G to C transversion at a splice acceptor site ca...
Identification of a one-base germline deletion (codon 888 del C) and an intron splice acceptor site polymorphism in hMSH2 Lisa A. Cannon-AlbrightSwensen, J, Lewis, CM, and Cannon-Albright, LA Identification of a one-base germline deletion (codon 888 del C) and an intron splice acceptor ...
Hancock DB, Reginsson GW, Gaddis NC, Chen X, Saccone NL, Lutz SM, et al. Genome-wide meta- analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine depen- dence. Transl Psychiatry. 2015; 5:e651. doi: 10.1038/tp.2015.149 PMID: 26440539....
The p53 transcription factor is a key tumor suppressor and a central regulator of the stress response, which has been a subject of intense research for over 30 years. Recently, a zebrafish line which carries splice site mutation (G>T) in intron 8 of p53 gene (p53 hu888 ), encoding the...
SpirioL.GreenJ.RobertsonM.OtterudB.SheldonHowseingentaconnectHuman Genetics BerlinSpirio L, Green J, Robertson J et al . The identical 5´splice-site acceptor mutation in five attenuated APC families from Newfounland demonstrates a founder effect. Hum Genet 1999;105:388-398....