RESULTS: This manuscript presents a novel publicly available splice site prediction tool named SpliceMachine that (i) shows state-of-the-art prediction performance on Arabidopsis thaliana and human sequences, (ii) performs a computationally fast annotation and (iii) can be trained by the user on ...
SpTransformer provides a powerful tool to guide biological and clinical interpretations of human diseases.Similar content being viewed by others Transformers significantly improve splice site prediction Article Open access 04 December 2024 A deep learning approach to identify gene targets of a ...
The selection of splice prediction tools included CADD, DSSP, GeneSplicer, MaxEntScan, MMSplice, MTSplice, NNSPLICE, SPIDEX, SpliceAI, SpliceRover and SpliceSiteFinder﹍ike. The best performing splice prediction tool for the different variants was SpliceRover for ABCA4 NCSS variants, SpliceAI for ...
In this paper, we introduce Splam, a new deep learning approach to splice site prediction in which the system learns to recognize paired donor and acceptor sites from genomic sequences. In comparison to SpliceAI, our method uses a much shorter flanking context sequence to predict splice sites, ...
Conclusion: Based on CNN, we have proposed a new ab initio splice site prediction tool, SpliceFinder, which generates less false positives and can detect non-canonical splice sites. Additionally, SpliceFinder is transferable to other species without retraining. The source code and additional ...
Based on CNN, we have proposed a new ab initio splice site prediction tool, SpliceFinder, which generates less false positives and can detect non-canonical splice sites. Additionally, SpliceFinder is transferable to other species without retraining. The source code and additional materials are availa...
Neural Network Splice Site Prediction Tool, SplicePort and NetGene2) and additional analyses (Single Amino Acid Polymorphism database, analysis of conservation... E Usifo,SEA Leigh,RA Whittall,... - 《Annals of Human Genetics》 被引量: 0发表: 2012年 Eight SNVs in NF-kappa B pathway genes...
produceaccuratesplice-sitepredictiononhuman pre-mRNAsequencedata.Inthiswork,wepresenta web-basedinteractivetool,SplicePort,whichallowsthe usertoexploretheFGAfeaturesandallowstheuserto makesplice-sitepredictionsforsubmittedsequencesbased onthesefeatures.
These features are then used as input in SVM for splice site prediction using a polynomial kernel. Positional, compositional and dependency features were extracted for the true and false splice sites and were used as input in SVM classifiers [23]. EFFECT uses a two-stage process, where a set...
Additionally, we offer an open-source stand-alone prediction tool allowing, for instance, the integration in other gene finder systems. The predictions, data sets and the stand-alone prediction tool are available for download on the supplementary websitehttp://www.fml.mpg.de/raetsch/projects/...