Spironolactone is available in 25- and 50-mg tablets. Typical dosages for cardioprotection range from 6.25 to 25 mg once or twice daily and generally fall within a dosage range of 0.5 to 2 mg/kg daily. Dosages are somewhat empiric and related to severity of CHF and patient size; in huma...
In a single blind crossover trial, spironolactone (50 mg twice a day), and hydrochlorothiazide (50 mg twice a day) were equally effective hypotensive agents in 16 patients with untreated essential hypertension. The addition of alpha-methyldopa (250 mg three times a day) to each agent produced...
Spironolactone, an aldosterone-, and competitive androgen-receptor-antagonist and 5-alpharductase- inhibitor, indicated for the treatment of androgen dependent hirsutism, ideally in doses of 50 to 200 mg per day accompanying the intake of oral contraceptives with the same seven day break in between...
Used as a fourth-line add-on therapy for hypertension not responding to the combination of three more usual antihypertensive drugs: Supply Spironolactone (generic) Tablets 25mg, 50mg, 100mg, 28 days @ 200mg each morning = $50. Spironolactone oral suspension can also be prepared locally for ...
He was started with spironolactone 100mg twice a day. He developed painful gynaecomastia and his spironolactone was changed to eplerenone. However, it was inadequate to control his hypertension or hyperkalaemia. He was added with spironolactone 25mg twice a day which controlled his hypertension ...
aldosterone formation; however, clinical studies in patients with moderate or severe heart failure indicate addition of low-dose (25–50 mg daily) spironolactone to standard therapy (e.g., an ACE inhibitor and a loop diuretic with or without a cardiac glycoside) decreases mortality and ...
DOSAGES. The dosage of spironolactone for acne is25-200 mg/day in one to two divided doses. A study that used 50 mg spironolactone twice a day on Days 5 through 21 of women's menstrual cycle had a high rate of success with low incidence of side effects (Harper, 2006). ...
Spironolactone (100 mg) for 25 days in each menstrual cycle was assessed over 6 months for treatment of hirsutism in 35 patients. Five patients withdrew due to either nausea or polymenorrhea. the latter problem was encountered in 16 patients. Of the 30 remaining patients, 17 had a significant...
Dose: 50 to 100 mg orally per day divided once to twice daily Maximum: 200 mg/day Hyperandrogenism Dose: 50 mg orally twice daily Hypertension Dose: 12.5 to 50 mg orally daily Maximum: 100 mg Primary Hyperaldosteronism Dose: 100 to 400 mg/day preoperatively Use the lowest effective...
Pig serum (PS) (0.5 mL, twice a week, ip) or vehicle-administered rats for 12 weeks were used as rats with hepatic fibrosis or control rats, respectively. Rats given PS were treated with SPL (50 mg/kg/day, sc) for 12 weeks. Hepatic fibrosis, using picro-sirius red staining and ...