Four were located in the subcutaneous tissues of the upper back or posterior neck and one behind the left ear. They exhibited a spectrum of histological growth patterns. Electron microscopy demonstrated two distinct populations of tumor cells; one, a spindled non-fat-storing mesenchymal cell and ...
is composed of fusiform cells orientated in bundles and whorls (Fig. 38.3A).Spindle cellshave variable amounts of fibrillar cytoplasm, and their borders are difficult to distinguish because the cells adhere to each other. Originally,spindle cellmelanomaswere divided into spindle A and B types. T...
Spindle cell neoplasms are characterized by the presence of spindle-shaped cells in histopathology sections. A two years old male German shepherd dog was presented with the history of epistaxis, firm and smooth exophytic mass on the palate, and dysphagia. Physical examination of the mass revealed ...
Nasal endoscopy showed a polypoid tumor measuring 3×3cm at the nasal septum in the right nasal cavity, and an excisional biopsy was performed. Computed tomography (CT) demonstrated the nasal tumor extended to the maxillary sinus. Histologically, the tumor consisted of malignant spindle cells with...
Myoepithelial cells are normally located between the epithelial cells and the basal lamina of secretory elements of exocrine glands. Their role in the hist... MP Foschini,V Eusebi - 《Virchows Archiv》 被引量: 368发表: 1998年 Myoepithelial carcinoma of soft tissue in children: an aggressive ...
Numerous cytokinesis factors are also localized to the spindle pole body, a medial microtubule organizing center structure associated with the nuclear envelope. The IQGAP Rng2p and the polo kinase Plo1p are located on the spindle pole body and have roles in ring assembly and placement 49,57. Ma...
What is the role of the mitotic spindle? Mitotic spindle formation is a critical event that takes place during prophase. These spindle fibers are necessary to equally divide the chromosomes in the parent cell so that equal, identical copies are found in both daughter cells.What...
1a, b). Then we treated HeLa cells with 0.25 μM MLN8237 to inhibit the kinase activity of Aurora A without influencing activity of Aurora B. More strikingly, we found that Aurora A inhibition did not shorten the spindle length in NuMA-depleted cells (Fig. 1a, b and Supplementary ...
However, not all cells showed robust integrin adhesions, and closer examination revealed these cells to be mitotic. In Fig. 1b (left image), two cells in the same field are shown (one non-mitotic cell, Cell 1, and another undergoing mitosis, Cell 2; further example shown in Supplementary...
We have microinjected biotinylated tubulin into mitotic fibroblast cells to identify the sites in the spindle at which new subunits are incorporated into m... T Mitchison,L Evans,E Schulze,... - 《Cell》 被引量: 1472发表: 1986年 Phosphoproteome analysis of the human mitotic spindle During cel...