Many large, phagocytic human macrophages expressed membrane hCD4 within the lesion. Rat CD4+macrophages are found at sites of myocarditis69, in tumors38and in the injured rat spinal cord32,33. In the mouse gut, CD4+macrophages also have unique ontogeny and function70,71. The CD4 co-receptor,...
1991. Transplantation of labeled fetal spinal cord fragments into juvenile myelin-deficient rat spinal cord. Anat Rec 229:138 -143.Rosenbluth, J., M. Hasegawa, N. Shirasaki, C. L. Rosen, and Z. Liu. 1990. Myelin formation after transplantation of normal fetal spinal cord fragments or ...
The spinal cord accounts for the main communication pathway between the brain and the peripheral nervous system. Spinal cord injury is a devastating and largely irreversible neurological trauma, and can result in lifelong disability and paralysis with no
Fig. 1. Ependymal cells appear at mid-embryonic stage in the developing mouse spinal cord. (A) Representative coronal section images of YFP labeled ependymal cells around the central canal (dashed lines) of tamoxifen recombined FoxJ1-CreERT2::YFP. YFP expression is induced by tamoxifen at E13....
In transgenic mice expressing green fluorescent protein (GFP) under crym regulatory elements (crym-GFP), comprehensive and near complete CST labeling is achieved throughout the spinal cord. Bilateral pyramidotomy eliminated the 17,000 GFP-positive CST axons that were reproducibly labeled in brainstem...
Time-dependent changes in Bolton-Hunter-labeled125I-substance P binding occurred in the dorsal horn of the spinal cord following unilateral adjuvant-induced inflammation in the hindpaw of the rat. Inflammation was characterized by measures of edema and hyperalgesia. Edema and hyperalgesia were both pr...
Up to 5 μl of PBNC-labeled MSCs suspended in PBS at 10k cells/μl were directly injected into the spinal cord per the clinical procedure at a rate of 16 nl/sec using a 33 G syringe attached to an ultra-micropump (World Precision Instruments). 2.6. Real-time US/PA imaging during ...
Screws should approach the opposite cortex but should not breach it. In anterior-plate screw fixation, the screws may back out and impinge soft tissue (e.g. great vessels, trachea and esophagus) or overpenetrate the posterior cortex and impinge on the cord. These complications can be prevented...
Mn (III) tetrakis (4-benzoic acid) porphyrin scavenges reactive species, reduces oxidative stress, and improves functional recovery after experimental spinal cord injury in rats: comparison with methylprednisolone Danxia Liu, Yichu Shan, Lokanatha Valluru & Feng Bao BMC Neuroscience volume 14, Articl...
Vascular endothelial cells are pivotal in the pathophysiological progression following spinal cord injury (SCI). The UTX (Ubiquitously Transcribed Tetratripeptide Repeat on Chromosome X) serves as a significant regulator of endothelial cell phenotype. Th