spinal cord compressionSummary Spinal cord compression is one of the most dreaded complications of metastatic cancer, occurring in 5-10% of all cancer patients during the course of their disease requiring urgent oncologic care. The pathophysiology of metastatic spinal cord compression (MSCC) is ...
Dr. Zipser is a research group leader with a focus on CSF pressure diagnostics and the pathophysiology of spinal cord compression. He received funding from the Swiss Paraplegia Foundation, International Foundation for Research in Paraplegia, Olga Mayenfisch Foundation, AO Spine and Balgrist Foundation....
Spinal cord infections should be distinguished from postviral inflammatory syndromes, including postviral transverse myelitis. Additionally, epidural abscesses may cause spinal cord compression. Neurodegenerative Disorders of the Spinal Cord At this time, mutations of more than 50 genes have been described...
macrophages activity and recruitment15. However, there is no information on the effects of progressive compression of the spinal cord on NeP-related pathological changes, such as glial activation and BSCB dysfunction. In this regard, our group published a series of studies conducted in mice with sp...
Pathophysiology of Thoracic Myelopathy Conclusion As the rigid transition zone between the cervical andlumbar spine, thethoracic spineis subjected to distinct biomechanics and deformative stresses. The unique orientation of the facets and sternocostal stabilization reduce the amount of dynamic compression to...
SPINALCORDINJURIES Anatomy&Pathophysiology JCKing Definition Insulttospinalcordresultinginachange, inthenormalmotor,sensoryorautonomicfunction.Thischangeiseithertemporaryorpermanent. Mechanisms: Directtrauma Compressionbybonefragments/haematoma/discmaterial Ischemiafromdamage/impingementonthespinalarteries ...
Neoplastic disease that involves the spine and results in spinal cord or cauda equina compression may have devastating neurologic and functional consequences. Metastatic lesions are responsible for about 85% of neoplastic spinal cord compression cases, with the other 15% due to primary neoplastic lesions...
Retrospective study. Few studies have reported a relationship between central motor conduction time (CMCT), which evaluates corticospinal function, and degree of spinal cord compression in patients with myelopathy. Thus, there is no consensus on predicti
Pathophysiology Clinically relevant anatomy The spinal cord is formed by 31 segments protected by the bony vertebral column : The vertebral column is longer than the spinal cord . Depending on the level, vertebral level and spinal cord level are not necessarily the same. Cervical: 8 segments: ...
The pathophysiology of SCI includes primary injury and secondary injury; the former is usually a mechanical injury to the cord, and the latter is the consequence of cell and biological reactions to the primary injury, which involve the immune system, nervous system, vascular system, etc., includi...