Scientist Marcia Helena Borges is on the team working to develop a medicine to treat erectile dysfunction, inspired by spider venom. "The venom is only used to learn the properties of the molecule" which causes the priapism in bite victims, said Maria Elena de Lima, a UFMG researcher. Brazil...
The first phase is characterized by local effects, including a painful bite site, with swelling, redness, and fang marks. General symptoms during this first phase can also include perioral numbness, severe facial and tongue spasms, piloerection, nausea, vomiting, abdominal cramps, salivation, ...
Penile erectionSpider venomHistopathologyPhoneutria nigriventer spider bite causes priapism, an effect attributed to the peptide toxins Tx2-5 and Tx2-6 and involving nitric oxide. Tx2-6 (MW=5287) is known to delay the inactivation of Sodium channels in the same fashion as many other venom ...
Scientist Marcia Helena Borges is on the team working to develop a medicine to treat erectile dysfunction, inspired by spider venom. "The venom is only used to learn the properties of the molecule" which causes the priapism in bite victims, said Maria Elena de Lima, a UFMG researcher. Brazil...
As any surviving bite victim will attest, the devastating in vivo efficacy of the 42-residue lethal NaV channel toxin from the Australian funnel-web spider [42,127] plainly demonstrates how minute quantities of ICK peptides can be effective in humans. Should rapid proteolysis prove to be an ...
The condition caused by brown spiders, categorized as Loxoscelism, is associated with a series of clinical symptoms including cutaneous lesions, which spread gravitationally from the spider bite. The lesions are characterized by necrotizing wounds that are dark blue-violet in color and become ...