spICP-TOF-MS能够在极短时间窗口内测定单个颗粒的多元素组成，能够提供对应单个MNPs的主导组分及其共存金属的有效信息，从而揭示由MNPs引发肺细胞毒性的关键致毒组分及作用机理。单个MNPs的元素组成 基于spICP-TOF-MS技术，杨毅教授团队将MNPs按其元素组成分为两类（图1a）：单金属MNPs（sm-MNPs，仅检测到Fe）和多金...
As researchers begin to acquire larger multi-sample spICP-TOFMS datasets, robust batch-analysis programs are essential. To meet this need, our lab has developed and tested a set of spICP-TOFMS data analysis programs called "time-of-flight single particle investigator" or "TOF-SPI." These ...