本论文以蝉花为研究对象,建立了一套多球壳菌素分析技术平台;建立了同时测定蝉花中四种多球壳菌素类长链碱(myriocin-like long-chain bases,MLB)的方法;对蝉花鞘氨醇类长链碱(sphingoid long-chain bases,SLB)进行了代谢轮廓分析。
kinasesphingolipidsyeastSphingolipids are a family of eukaryotic lipids biosynthesized from sphingoid long-chain bases (LCBs). Sphingolipids are an essential class of lipids, as their depletion results in cell death. However, acute LCB supplementation is also toxic; thus, proper cellular LCB levels ...
RSK3, which belongs to the p90-S6K subfamily, was identified as a functional counterpart of Fpk1/2 in mammalian cells as the RSK3 gene functionally complemented the ISP-1-resistant phenotype of fpk1/2∆ cells. 展开 关键词: DIR screening long-chain base protein kinase sphingolipids yeast ...
翻译结果1复制译文编辑译文朗读译文返回顶部 鞘氨醇的长链碱防止肺部感染铜绿假单胞菌。 翻译结果2复制译文编辑译文朗读译文返回顶部 Sphingoid 长连锁设立通过 Pseudomonas aeruginosa 防止肺感染。 翻译结果3复制译文编辑译文朗读译文返回顶部 Sphingoid 长碳链基地防止铜绿假单胞菌肺部感染。
The long-chain bases (0.1 to 0.2mg) are reacted with freshly prepared aceticanhydridein methanol (1:4, v/v; 50mL) at room temperature for 20 minutes.n-Butanol (2mL) is added to facilitate the removal of the excessacetic anhydrideduring evaporation in a stream of nitrogen. ...
In a search for possible endogenous ligands of nuclear receptors that are activated by peroxisome proliferators (PPARs), a solid phase binding assay was developed employing recombinant mouse PPAR-α, containing a myc-epitope, a histidine repeat and a kinase A domain. After in vitro labelling with...
Our results suggest that these responses are mediated by long-chain sphingoid bases that accumulate as a result of FB1 action. Access through your organization Check access to the full text by signing in through your organization. Access through your organization ...
Moreover, we show that Izh2p-independent increases in sphingoid bases recapitulate the effect of Izh2p on FET3. Finally, our data indicate that the ... NY Villa,BR Kupchak,I Garitaonandia,... - 《Molecular Pharmacology》 被引量: 346发表: 2009年 Arabidopsis Sphingosine Kinase and the Effe...
Free sphingoid bases in microsomes from the brainstem and spinal cord were acylated or glycoslyated when incubated with acyl-CoA or UDP-glycoside. However, the reaction for the synthesis of ceramide was much greater and more rapid than that of glycoslysphingosine synthesis. In liver microsomes, ...
Accumulation of phosphorylated sphingoid long chain bases results in cell growth inhibition in Saccharomyces cerevisiae. Genetics 2000; 156:1519-1529. 54 Spiegel S, Milstien S. Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat Rev Mol Cell Biol 2003; 4:397-407. 55 Dietrich RA, Rich...