Detection of division non-disjunction of meiosis I and II in spermatogenesis of men with idiopathic infertility.superfecundationfetal reductionIVFgenetic analysisObjective: To present the first genetically proven identity of quintuplets in an IVF treatment cycle after transferring only two embryos. Design:...
Primordial germ cells, the founder cells of the germ line, develop through several immature stages by undergoing mitosis, meiosis and differentiation into the haploid spermatozoa, which carry only one set of chromosomes. Latest Research and Reviews Aberrant activation of chromosome asynapsis checkpoint ...
A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis. Proc Natl Acad Sci U S A. 2004;101(5):1327–32. Article PubMed PubMed Central CAS Google Scholar De Gendt K, Verhoeven G, Amieux PS, Wilkinson MF. Genome-wide identification of AR-...
respectively (Supplementary information, TableS4). We thus propose that, as development proceeds, spermatogonia gradually obtain the competency of commitment to meiosis. Interestingly, we also found that the FGF (fibroblast
All four ID proteins (ID1–4) are present in the testis, and ID4 has a particularly important role in spermatogonial stem cell fate determination. Several lines of evidence indicate that ID proteins are involved in meiosis; however, functional experiments have not been conducted to validate this...
Stem cells undergo four, five or six cell divisions prior to meiosis which includes a premeiotic S+G2 phase of 20 h followed by a long meiotic prophase (22 h). Spermatid differentiation requires 12–29 h. When they first appear, testes contain only proliferating spermatogonia; meiotic and ...
The onset of meiosis in prespermatocyte germ cells is similarly signalled by Sertoli cell-controlled paracrine mechanisms. Two of these mechanisms are worthy of mention: the copromotion of meiosis by retinoic acid (the active form of Vitamin A) and FSH (Zhang et al. 2011); and the pro...
Understand what spermatogenesis is. Learn and discuss meiosis in spermatogenesis, seminiferous tubules, sperm cell precursors, and the anatomy of...
Spermatogonia undergo mitotic division and increase in number. One of the resulting cells remains as a spermatogonium for further division, while the other cell becomes a primary spermatocyte. The primary spermatocyte undergoes meiosis I, resulting in two haploid secondary spermatocytes. Each secondar...
The expression pattern of H1t was different between the controls and the ClpP/ClpX cKO mice. More H1t positive cells were observed in the controls than the cKO groups. Majority of the H1t positive cells in the control group were at the late stages of meiosis, including round spermatids and...