Salivary microbial load has a limited influence on the ASD oral microbiome Since higher microbial load has been linked to poor oral hygiene and compromised oral health53,54, we estimated the microbial load in each subject (Methods) to investigate the potential impact of differences in oral hygiene...
Interestingly, blood vessels were shown to manifest sexual dimorphism due to the role of ERα in flow-mediated remodeling of resistance arteries [225]. In addition, the production of reactive oxygen by mitochondria could impact vascular lesions in a sex-specific manner [226]. Future studies will...
Furthermore, since the treatment of AI is administered by different health professionals, it may not be recognised as an aspect of a syndromic disease. We therefore suggest that paediatric patients presenting with sensorineural hearing loss, either in isolation or in combination with vision defects, ...
Differential oxidative stress and DNA damage in rat brain regions and blood following chronic arsenic exposure. Toxicol Ind Health. 2008;24:247–56. Article CAS PubMed Google Scholar Ježek P, Hlavatá L. Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism. ...
Department of Psychiatry, NICHE Lab, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands Sarah Durston & Bob Oranje Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty, Heidelberg University, Mannheim, Ger...
This has been of special concern in oncology due to the life-threatening consequences of lowered blood levels of drugs, and the potential for severe side effects when blood levels of a drug are increased or actions of herbal products reinforce those of conventional agents. Antiplatelet activity is...
Genomic DNA was extracted from whole blood or saliva using a Qiagen QIAamp DNA blood kit or tissue kit (Qiagen, Hilden, Germany). Raw WES data were generated and processed to BAM files at three sites (TableS1): The Broad Institute (ASD = 256, HC = 299) [11] using Illumina...
2 Mental Health Institute, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China. 3 Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington 98195, USA. 4 Children's Development Behavior Center, Third Affiliated Hospital of Sun ...
blood-urine pairs for isotopic Pb composition, indicating that urine can serve as an alternative for blood especially in new born infants and young children [96]. Fukui et al. suggested urine Pb to be a good alternative to blood Pb measurement on a group basis, in which the urine Pb was...
We extracted RNA from whole-blood samples of patients with deletions and measured transcriptome-wide expression. We evaluated two groups of genes in this analysis: (1) all genes within 1 Mb of the PennCNV-inferred deletion boundary but not included within it (“nearby” genes), and (2) ...