PROBLEM TO BE SOLVED: To provide a process for the easy and quick modification of the substrate specificity of an enzyme. SOLUTION: This process for the modification of the substrate specificity of an enzyme comprises (a) a step to introduce a DNA containing a copy of a gene coding for the...
Substrate specificity engineering is not intended to increase the catalytic turnover of a substrate, but exploited to promote the reaction of one substrate over another by governing accessibility to the active site of an enzyme. From: International Journal of Biological Macromolecules, 2019 ...
aAn Enzymatic Biofuel Cell is a specific type of fuel cell which uses biocatalysts to convert energy stored within chemicals into electrical energy. Enzymes are used to catalytically oxidise the fuel at the anode and reduce the ensuing oxidant at the cathode. The specificity of the enzyme reactions...
susceptibility to var.avenaedepend on an inhibitor-inactivating enzyme complex, and this is compared with the antibiotic-inactivating enzyme complex found in penicillin-producing moulds and resistant penicillinase-producing bacterial strains; such a complex may be concerned in other cases of pathogenic ...
Enantiospecificity is the ability of an enzyme to convert a racemic mixture into a particular enantiomer. The degree of specificity is interrelated with that of selectivity, which equation suggested by Lopez and coworkers (Lopez et al.1990): ...
A role for metabolite enantiomers in the evolution and integration of enzyme driven systems These include asparaginase, glutamate decarboxylase, histidase, lactate oxygenase, lactate dehydrogenase, dipeptidase and chymotrypsin isolated from a variety of species. Inhibition by the enantiomer or other stereois...
Specificity, mode of action and distribution of cholinesterases. VER SINCE the fugitive action of acetylcholine in vivo was first attributed to its destruction by an enzyme (35, 74)(named choline-esterase by the Stedmans, 121) a large amount of work has been carried out on the nature, mode...
With the excellent performance of SPA on the benchmark test, we want to evaluate the ability of SPA in real virtual screening test. The enzyme cyclooxygenase-2 (COX-2) was chosen as our target protein model which is the target of nonsteroidal anti-inflammatory drugs (NSAIDs) for reducing ...
A new product of linoleic acid oxidation by a flaxseed enzyme Although the products of lipoxidase activity have been known for some time, the function of this enzyme in plant metabolism is not known ( Tappel, 1963). This paper reports the isolation of an enzyme from flaxseed which utilizes ...
Two "classical" Old Yellow Enzymes from Chryseobacterium sp CA49: Broad substrate specificity of Chr-OYE1 and limited activity of Chr-OYE2 Two putative Old Yellow Enzyme (OYE) homologues, Chr-OYE1 and Chr-OYE2, were identified from the genome of Chryseobacterium sp. CA49 as new members of...