We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...
Tanabe T,Suzuki S,Hara K,et al.Cerebrospinal fluid and serum neuron-specific enolase levels after febrile seizures. Epilepsia . 2001... T Tanabe,S Suzuki,K Hara,... - 《Epilepsia》 被引量: 0发表: 2001年 A gain-of-function mutation in the sodium channel gene Scn2a results in seizures ...
The prevalence of cognitive impairment is higher in women with HIV (WWH) compared to men with HIV (MWH), possibly due to sex differences in immune function. Here we report sex differences in cerebrospinal fluid (CSF) immune markers in relation to cognitive performance. A subset of 83 PWH on...
Pores from the fourth ventricle open into a subarachnoid space that surrounds the brain. These ventricles are filled with a liquid, the cerebrospinal fluid (CSF), which also bathes the outside of the brain and cushions the organ in the cranial cavity. The CSF is secreted in part by a ...
of gross abnormalities in adult brain morphology11, apoptosis of post-mitotic cells in the adult SVZ was reduced12together with observed proliferative defects13. Recent research has also attributed other roles to TTR that might transcend its well-known TH distribution function.Do novoTTR synthesis ...
For each participant, a score was calculated for every biological process and molecular function GO term gene set using GSVA version 1.36.3. (Hänzelmann et al., 2013) based on the batch-corrected and normalized RNA-seq data. The distribution of these gene set scores across clusters was ...
is controlled by UAP56/URH49. UAP56 controls the export of long circRNAs (>1200nt) and URH49 is required for short circRNAs (<400nt) [14]. The m6A modification in circNSUN2 can facilitate its export [15]. In cytoplasm, circRNAs may function as microRNA sponges, interact with circRNA ...
Memory function often declines with age, and is believed to deteriorate initially because of changes in synaptic function rather than loss of neurons. Some individuals then go on to develop Alzheimer's disease with neurodegeneration. Here we use Tg2576 mice, which express a human amyloid-β precur...
We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...
Chronic neuroinflammation is a critical component in the progression of many neurodegenerative diseases, including AD [4]. Key neuroinflammatory effectors are microglia, the resident immune modulators of the brain. Microglial function is controlled by variants in AD risk genes (e.g.,TREM2,APOE,CLU,...