This review highlights the diversity of functions of DnaJ-like proteins by using specific examples of DnaJ-Hsp70 interactions with polypeptides in yeast protein-biogenesis pathways. 展开 关键词: Mitochondria Saccharomyces cerevisiae Escherichia coli Escherichia coli Proteins Saccharomyces cerevisiae Proteins ...
Transfection and feeding with chemically modified sugars can, in theory, alter the cellular transcriptome, leading to artefacts in protein expression and metabolic labelling. We performed transcriptomic analyses in cells transfected with either NahK/mut-AGX1 or empty plasmid, and fed with either DMSO ...
b Examples of existing spatial-omics data integration pipelines show (i) same-modality integration, (ii) cross-modality integration with shared features, and (iii) cross-modality multi-modal on the same cell. (i) is applied to remove the batch effect from both metabolite and protein datasets....
It is notable that six domains were found that were not associated previously with ePKs in other organisms, based on searches of the Pfam database and Genbank. Examples of proteins containing an ePK domain along with novel accessory domains are shown in Figure 2. The unusual domains include th...
Human α-galactoside or Bacillus anthracis protective antigen are examples of biotherapeutic proteins whose solubility has been successfully redesigned by using SolubiS, reducing their aggregation propensity while maintaining their functional activity [106]. Such approximation has also been translated to the...
In particular, the invention is illustrated by examples of chimeric proteins of a cell-targeting moiety and an apoptosi... S Yarkoni,A Ben-Yehudah,Y Azar,... 被引量: 0发表: 2005年 加载更多来源期刊 Plant Cell 研究点推荐 BASIC PENTACYSTEINE Proteins Target Genes MADS Domain Complex 站内...
The atomic coordinates of EndoSE235A-Fc have been deposited in the Protein Data Bank (PDB) under the accession code 8A64, and the cryoEM map are deposited in the Electron Microscopy Data Bank (EMDB) under the accession code EMD−15205. Previously published PDB structures used in this stud...
Gag, or group specific antigen, is the major structural protein (of HIV-1 and all other retroviruses) and comprises about 50% of the mass of a viral particle. From: Trends in Microbiology, 2013 About this pageSet alert Discover other topics On this page Definition Chapters and Articles Relat...
Protein glycosylation is a highly important, yet poorly understood protein post-translational modification. Thousands of possible glycan structures and compositions create potential for tremendous site heterogeneity. A lack of suitable analytical methods
We found several examples of such cases. For example, we identified a novel SUMOylation site in DNA-PK (PRKDC, P78527), which would have been in a tryptic peptide of length 57 (Fig. 2b), and another in Sp100 (P23497), which would have been a tryptic peptide of only six amino ...