and, moreover, allows systematic identification of cell-type-specific mechanisms of genomic folding through in silico genetic screening (ISGS). Applying ISGS to T cell acute lymphoblastic leukemia (T-ALL) cells and normal T cells, we identified ...
School of Chemistry & Institute of Biotechnology, The University of Manchester, Manchester, M1 7DN, UK Peter Both, Kun Huang, Fabio Parmeggian & Sabine L. Flitsch Contributions A.C., B.C., T.R., V.L.B., A.M., G.B.-T., H.F., A.G.-G., A.A. performed experiments; Z.L...
The best examples are biotechnology and computer software. In biotechnology cases, the Federal Circuit has bent over backwards to find biotechnological inventions nonobvious, even if the prior art demonstrates a clear plan for producing the invention. On the other hand, the court has imposed ...
The protocal for RNA-seq library construction of the embryo and endosperm samples were the same as in our previous work [42]. Total RNA was extracted using a Quick RNA Isolation Kit (Huayueyang Biotechnology of Beijing). RNA-seq libraries were constructed and sequenced using the Illumina NovaSeq...
Animal models: bridging cross-species variation through animal biotechnology Nayaab Laaldin, ... Mustafeez Mujtaba Babar, in Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries, 2020 8.5.2 Importance of specific pathogen-free animals in research • SPF animals are free o...
BioTechnology. 1993, 11: 1026-1030. 10.1038/nbt0993-1026. Article CAS PubMed Google Scholar Higuchi R, Dollinger G, Walsh PS, Griffith R: Simultaneous amplification and detection of specific DNA sequences. BioTechnology. 1992, 10: 413-417. 10.1038/nbt0492-413. Article CAS PubMed Google ...
Microarray data have been deposited in the National Center for Biotechnology Information Gene Expression Omnibus database (http://www.ncbi.nlm.nih.gov/geo/, accession number GSE46076). In this paper, upregulation of a gene in a given cell type means upregulation in comparison to the other ...
While there are an increasing number of prominent examples of parasitic behavioral manipulation [2]–[6], the molecular mechanisms of host manipulation remain poorly understood [3]–[5],[7]–[11]. One example where significant progress has been made is the parasite Toxoplasma gondii. Infected ...
Single-cell RNA-sequencing has become a powerful tool to study biologically significant characteristics at explicitly high resolution. However, its application on emerging data is currently limited by its intrinsic techniques. Here, we introduce Tissue-A
etc. are just a few examples of the many variables that affect the quality and quantity of secondary metabolite content in botanicals17.P. longumchemotypes were collected for this study from 10 different districts in West Bengal, India, separated geographically. As a result, the distinct geographic...