Specific COX-2 inhibitors,from bench to bedside[A].London:William Harvey Press,1997.127-133.Isakson P,Zweifel B,Masferrer J. Specific COX-2 inhibitors,from bench to bedside[A].London:William Harvey Press 1997.Isakson P, Zweifel B, Masferrer J, Koboldt C, Seibert K, Hubbard R, Geis S ...
Rehman Q, Sack KE: When to try COX-2-specific inhibitors. Safer than standard NSAIDs in some situations. Postgrad Med 1999; 106: 95-7, 101-2, 105- 6.Rehman Q,Sack KE.When to try COX-2-specific inhibitors:safer than standard NSAIDs in some situations[J].Postgrad Med,1999,106:95...
AR1 ASSESSING THE COST-EFFECTIVENESS OF COX-2 SPECIFIC INHIBITORS FOR ARTHRITIS IN THE VETERANS HEALTH ADMINISTRATIONdoi:10.1016/S1098-3015(10)62075-XM SchaeferML DeLattreX GaoJM StephensA MorrealeValue in HealthSchaefer M, DeLattre M, Gao X, Stephens J, Botteman M, Morreale A. Assessing the...
However, further experimental and clinical studies will be necessary, mainly with regard to new untypical side effects to show whether or not selective COX-2 inhibitors are of clinical value in the treatment of rheumatic disorders. 展开 关键词: chylous tenosynovitis Mycobacteria kansasii ...
Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice. To clarify the role of mitogen-inducible cyclooxygenase (COX-2) in the development of malignant tumors, we investigated the effects of COX-2 inhibitors on ... H Sawaoka,S Kawano...
Alternative splicing, a fundamental step in gene expression, is deregulated in many diseases. Splicing factors (SFs), which regulate this process, are up- or down regulated or mutated in several diseases including cancer. To date, there are no inhibitors
At present, the COVID-19 treatment armamentarium is largely represented by antiviral agents and immunotherapeutic agents that modulate the host immune response, including nonspecific and broad modulators, such as corticosteroids, or very targeted inhibitors, such as inhibiting one specific cytokine or kina...
(HRD), frequently caused by mutations in theBRCA1andBRCA2tumour suppressor genes (TCGA2011; Denkert et al.2022; Morgan et al.2023a). Almost 20 years ago, a major advance was the discovery thatBRCA1/2-mutant cells are exquisitely sensitive to PARP-1/2 inhibitors (PARPi) (Bryant et al....
Currently 2 difference classes of cyclooxygenase (COX)-2 inhibitors, coxibs and relatively selective COX-2 inhibitors, are available for patients requiring nonsteroidal anti-inflammatory drug (NSAID) therapy; their gastroprotective effec... M Yang,H Wang,M Zhao,... - 《Medicine》 被引量: 4发表...
The Second Generation of COX-2 Inhibitors Parecoxib as a parenteral, highly selective COX-2 inhibitor has the potential to become the NSAID of choice for treatment of postoperative pain. In ... Dr,Dirk,O.,... - 《Drugs》 被引量: 188发表: 2003年 Intravenous or intramuscular parecoxib for ...