Notably, secretory pathway genes were highly expressed in HGD-5 animals including ubc-13, an orthologue of human UBE2N, sel-1, an orthologue of human SEL1L, cdc-48.2, an orthologue of human VCP, ubxn-4, an orthologue of human UBXN4, der-2, an orthologue of human DERL2, and sel-11...
35. To assess whether HGD influences food intake in D5 worms, we measured the change of OP50 density in liquid culture after 3 days incubation36(Fig.1d). In WT worms, bacteria levels were significantly higher in HGD-1 while slightly higher in HGD-5 when compared to ND. Next, we measur...