Lysosomes are vital organelles vulnerable to injuries from diverse materials. Failure to repair or sequester damaged lysosomes poses a threat to cell viability. Here we report that cells exploit a sphingomyelin-based lysosomal repair pathway that operate
Treatment of resistant infectious diseases poses a significant threat to human health, in particular those arising from the emergence of multidrug-resistant pathogenic bacteria. This has prompted significant efforts in the development of new small molecule antibiotics1,2,3,4, resulting in a resurgence ...
pesticide application is also high in this region. Heavy pesticide application poses deleterious effect on non-target beneficial microorganisms, humans and other life forms. Further
Sims, A. Giles, H.A. Campbell, M.M. Musonda Metabolic trade-off between locomotion and detoxification for maintenance of blood chemistry and growth parameters by rainbow trout (Oncorhynchus mykiss) during chronic dietary exposure to copper Aquat. Toxicol., 47 (1) (1999), pp. 23-41 View ...
[11], and the results are reported inTable 1andTable 2. The visual inspections of the produced docking poses (10 poses/molecule) for the binding interactions with various amino acid residues lining the active site of 3 target proteins crystal structures are listed inTable 2and are represented ...