分子时代学病理——SOX10基因 病理专业杂志《 J Clin Pathol》专栏-《Gene of the Month》,每期选择一个基因进行详细的介绍,相关内容详尽,对病理诊断实践帮助较大。本期我们选择2023年6月介绍基因SOX10的一期内容编译介绍给大家。 SOX10简介 转录因子中的SOX家族对于胚胎发育过程中细胞分化的确定极为关键。目前在小...
分子时代学病理 病理专业杂志《 J Clin Pathol》专栏-《Gene of the Month》,每期选择一个基因进行详细的介绍,相关内容详尽,对病理诊断实践帮助较大。本期我们选择2023年6月介绍基因SOX10的一期内容编译介绍给大家。 SOX10简介 转录因子中的SOX家族对于胚胎发育过程中细胞分...
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins...
Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. 包装清单: 产品编号 产品名称 包装 L31097 SOX10 Knockout HEK293T Cells 1支/瓶 — 说明书 1份 保存条件: 对于细胞培养瓶或离心管运输的活细胞,室温3-5天有效;对于干冰运输的冻存细胞,液氮保存,长期有效...
transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease...
Gene ID: 6663 种属 Homo sapiens 基因序列编号: NM_006941.4 基因描述 Homo sapiens SRY-box transcription factor 10 (SOX10), mRNA DNA编码区: atggcggaggagcaggacctatcggaggtggagctgagccccgtgggctcggaggagccc cgctgcctgtccccggggagcgcgccctcgctagggcccgacggcggcggcggcggatcg ggcctgcgagccagcccggggccaggcgagct...
转录因子SOX10抗体是用转录因子SOX10经适当修饰后免疫化,然后用protein A和抗原多肽亲和柱经过两步纯化得到的高纯度多克隆抗体。 SRY-box containing gene10(SOX10)基因的启动子区在肿瘤中存在异常的高甲基化,是潜在的抑癌基因。SOX10属于SOX家族,该家族成员的共同特点是含有和Sry(sex determinationregion of Y chro...
Conclusion This study identified a new mutation of SOX10 gene, which enriched themutation spectrum of this gene. And the analysis of clinical characteristics of this patient also expanded thephenotype of this gene. This study provided a reference for clinical diagnosis and genetic diagnosis of PCW...
Sox10 Gene is Required for the Survival of Saccular and Utricular Hair CellsBackground:. Pathological changes of the cochlea and hearing loss have been well addressed in Waardenburg syndrome (WS). However, the vestibular organ malformation in WS is still largely unknown. In this study, the ...
and mutations in the SOX-10 gene are linked to Waardenburg-Shah and Waardenburg-Hirschsprung disease. Anti-SOX-10 has been shown to be sensitive for conventional, spindled, and desmoplastic melanoma, and has been used to detect metastatic melanoma and nodal capsular nevus in sentinel lymph nodes...