This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins...
病理专业杂志《 J Clin Pathol》专栏-《Gene of the Month》,每期选择一个基因进行详细的介绍,相关内容详尽,对病理诊断实践帮助较大。本期我们选择2023年6月介绍基因SOX10的一期内容编译介绍给大家。 SOX10简介 转录因子中的SOX家族对于胚胎发育过程中细胞分化的确定极为关键。目前在小鼠和人类已发现了20种不同的...
BACKGROUND: Sry-related HMG-BOX gene 10 (SOX10), a nuclear transcription factor that plays an important role in schwannian and melanocytic cell differentiation, has recently been shown to be a useful marker in the diagnosis of melanocytic and schwannian tumors. Fibroblasts and histiocytes that ...
protein-coding gene 同源简称(alias symbol) DOM|WS4|WS2E 基因家族代码(gene_family_id) 757[HGNC][GenScript] omim代码 602229 entrez码 6663[Vega] ensembl基因码 ENSG00000100146[Ensembl] 基因家族(gene family) SRY (sex determining region Y)-boxes ...
《J Clin Pathol》专栏《Gene of the Month》精选介绍基因SOX10，探讨其在胚胎发育、病理诊断与肿瘤中的重要作用。SOX10，作为转录因子SOX家族的一员，尤其在SoxE组别中，对于胚胎发育过程中的细胞分化至关重要。这一基因在小鼠和人类中具有20多种不同的变体，参与神经嵴细胞迁移、软骨形成、神经胶质形成...
[0072]3)用Bsal酶切质粒pUCkan-T7-sgRNA质粒(参考文献Shen,Β·etal., Generationofgene-modifiedmiceviaCas9/RNA-mediatedgenetargeting.Cell Res. 23,720-723(2013)),将酶切产物凝胶电泳后回收线性质粒片段;[0073] 4)将上述获得的双链DNA片段与线性质粒片段通过T4DNA连接酶相连接,并将连 接产物转化至感受态...
All SOX10 reagents are produced in house and quality controlled, including 2 SOX10 Gene. All SOX10 reagents are ready to use. All SOX10 Reagents SOX10 cDNA Clones (2) SOX10 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each SOX10...
Gene ID: 6663 种属 Homo sapiens 基因序列编号: NM_006941.4 基因描述 Homo sapiens SRY-box transcription factor 10 (SOX10), mRNA DNA编码区: atggcggaggagcaggacctatcggaggtggagctgagccccgtgggctcggaggagccc cgctgcctgtccccggggagcgcgccctcgctagggcccgacggcggcggcggcggatcg ggcctgcgagccagcccggggccaggcgagct...
Conclusion This study identified a new mutation of SOX10 gene, which enriched themutation spectrum of this gene. And the analysis of clinical characteristics of this patient also expanded thephenotype of this gene. This study provided a reference for clinical diagnosis and genetic diagnosis of PCW...
蛋白别名:dominant megacolon; dominant megacolon, mouse, human homolog of; MGC15649; Protein SOX-21; SRY; SRY (sex determining region Y)-box 10; SRY box 10; SRY-box containing gene 10; SRY-related HMG-box gene 10; Transcription factor SOX-10; Transcription factor SOX-M ...