Expression of ectodermal-enriched genes such as Nestin, Ck17 or Pax3, as well as endodermal genes such as Foxa2, HFN4 or albumin, was not affected by OCT4 overexpression or by the absence of NIPBL (Fig. 8c). Discussion Our findings show that the OCT4/SALL4 duo is a key complex ...
Direct AKT targets implicated in transcription control include CREB and Forkhead box factors (FoxA1 and FoxO family [15]). Cellular fractionation and Western blot analysis (Fig. 1a) showed no difference in the levels and localization of those factors, suggesting that Sox10 is likely activated ...
Led by Tom Seaver and Jerry Koosman, the Mets became the first expansion team to win a title, setting a template for four new teams in 1969—the Montreal Expos, San Diego Padres, Kansas City Royals, and Seattle Pilots. Cleon Jones bent his knees to catch the final out, and scores of ...