In the individual patient, the maximally tolerated dosage was limited by the emergence of side effects or prolongation of the corrected QT (QTc) interval to >0.55 s. 1.5. Criteria for discharge on d,l-sotalol therapy and follow-up. Long-term oral d,l-sotalol was used in those patients ...
Amiodarone tended to be superior to propafenone, though its long-term efficacy was limited by adverse side effects.Kochiadakis GEMarketou MEIgoumenidis NEChrysostomakis SIMavrakis HEKaleboubas MDVardas PEPACE: Pacing and clinical electrophysiology...
308 patients (mean age 60 years, 70% men, 48% with heart disease) with sustained atrial fibrillation (n = 251) or atrial flutter (n = 57) (duration three hours to 45 days) were randomised to three groups to receive a 10 minute infusion of 1 mg ibutilide (n = 99), 2 mg ib...
(mean age 60 years, 70% men, 48% with heart disease) with sustained atrial fibrillation (n=251) or atrial flutter (n=57) (duration three hours to 45 days) were randomised to three groups to receive a 10 minute infusion of 1mg ibutilide (n=99), 2mg ibutilide (n=106), or 1.5...
Historically it has been advised that some drugs that can affect the heartbeat should not be used in those with HCM, leaving people with HCM to be treated with other drugs that have undesirable side effects. We studied HCM patients who had been prescribed two of the drugs that were advised...
The efficacy and tolerability of propafenone and sotalol in the prevention of paroysmal atrial fibrillation (AF) were assessed in a doubleblind placebo-controlled study over 1 year. Participants included 300 patients (168 men and 132 women) with an average age of 52.3 years. Patients were ...