Antacids given 2 hours or less before sotalol may reduce the bioavailability Reduce or discontinue therapy if quarterly prolongation, slow heart rate (bradycardia), atrioventricular block, low blood pressure (hypotension), worsening of heart failure occur Do not discontinue abruptly; acute exacerbation o...
The comparative study of effects of Wenxin Granules and Bisoprolol on treating patients with increasing heart rate and functional ventricular premature beat; 稳心颗粒与比索洛尔治疗心率增快型功能性室性早搏的对比研究 更多例句>> 3) Sotalol ['səutəlɔl] 索他洛尔 1. Comparative Analysis and...
produced etectrophysiologic changes that were consistent across studies: 10–16% increase in right ventricular effective refractory period (ERP), 4–8% increase in corrected QT interval (QT), and 17–30% increase in sinus cycle length (corresponding to a 15–23% decrease in heart rate). In...
Heart RateSotalol is a unique beta-adrenergic blocking agent with additional actions characteristic of Vaughn-Williams class III antiarrhythmic agents in experimental models. To test the efficacy of Sotalol to suppress ventricular arrhythmias, a 6 week parallel, placebo-controlled outpatient study of two...
Sotalol is a medication used to treat irregular heartbeat. Though effective, sotalol can cause life-threatening complications...
surgery based on a new risk prediction algorithm.In a retrospective analysis of a prospective randomized trial, a model for risk prediction was determined based on clinical data of the control group (A; n = 107) and tested in a test group (B; n = 107, treated with low dose sotalol). ...
Cardiac output, contractility (dP/dT(max)), diastolic performance (dP/dT(min)), and heart rate were compared between groups over time by linear mixed modeling. Results: Compared with placebo, sotalol decreased contractility by an average of 24% (P < .001) over the infusion period, as did...
The defined efficacy criterion (鈮 75% VPC suppression) was achieved by 6% of patients taking placebo, 34% of patients taking low- and 71% of patients taking high-dose sotalol. Sotalol was generally well tolerated, especially with the lower dose. Heart rate decreased, and PR and QTc ...
These changes were independent of heart rate. CONCLUSIONS--Treatment with low dose sotalol reduces high frequency P wave energy but does not change P wave duration. These results are consistent with the class III effect of the drug and suggest that signal averaging of the surface P wave may ...
Other variables investigated included QTc interval measured on maternal electrocardiogram before and after initiation of antiarrhythmic therapy, fetal heart rhythm and heart rate pre- and postnatally, oral maternal drug therapy used, time to conversion to sinus rhythm (SR), percentage of fetuses ...