Long-term administration of beta-blockers should not be routinely discontinued before major surgery; however, the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks ofgeneral anesthesiaand surgical procedures Formulations indicated for ventricular and atrial arrhythm...
Simon A, Berman E: Long-term sotalol therapy in patients with arrhythmias. J Clin Pharmacol 19: 547, 1979Simon A, Berman E. Long-term sotalol therapy in patients with arrhythmias.] Clin Phamzacol 1979; 19: 547-556.Simon A, Berman F: Long term sotalol therapy in patients with ...
Sotalol can be used safely and effectively in the long-term treatment of life-threatening ventricular arrhythmias following a myocardial infarction. However, experience in the use of Sotalol to treat cardiac arrhythmias in the early phase of recovery from acute MI is limited and at least at high ...
Sotalol produced an 88,5% (P < 0,001) reduction in ectopic beat frequency at the optimal titrated dosage, with relatively few physical or biochemical side-effects. In situations where ventricular anti-arrhythmic therapy is deemed necessary, especially if long-term use is considered, sotalol seems...
Both prevention of reinducible arrhythmia and the suppression of spontaneous arrhythmias on Holter recordings are predictive of a long term favourable clinical outcome. In patients with reduced ejection fractions, sotalol depresses ventricular function less than conventional β- blockers. The side effects ...
CONCLUSIONS: Amiodarone and propafenone were superior to sotalol in maintaining long-term normal sinus rhythm in patients with atrial fibrillation. Amiodarone tended to be superior to propafenone, though its long-term efficacy was limited by adverse side effects.Kochiadakis GEMarketou MEIgoumenidis NE...
The effects of long term (4 weeks) treatment with oral metoprolol (100 mg twice daily) and sotalol (160 mg twice daily) on ventricular repolarisation time were compared in a double blind crossover study in 20 patients post-infarction. For QT interval studies transoesophageal atrial pacing was...
Both prevention of reinducible arrhythmia and the suppression of spontaneous arrhythmias on Holter recordings are predictive of a long term favourable clinical outcome. In patients with reduced ejection fractions, sotalol depresses ventricular function less than conventional 尾- blockers. The side effects ...
In a randomized study, the Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) trial , sotalol was associated with an increased in-hospital efficacy prediction rate (by Holter monitor or electrophysiologic study), reduced long-term arrhythmic recurrence rate with superior tolerance, ...
Current Therapeutic Research. 1995;56:1154-68.Bellandi F, Dabizzi RP, Niccoli L, Cantini F. Propafenone and sotalol in the prevention of paroxysmal atrial fibrillation: long-term safety and efficacy study. Current Therapeutic Research. 1995;56:1154-68....