A long-acting beta-blocker drug used to treat irregularity of the heart action. Brand names are Beta-Cardone and Sotacor. Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005 Want to thank TFD for its existence?Tell a friend about us, add a link to this page, or visitthe...
OBJECTIVES: To evaluate the effect of sotalol on heart rate (HR), QT interval, atrial fibrillatory rate, and success of cardioversion in horses with naturally occurring chronic atrial fibrillation (AF). ANIMALS: Twenty-eight horses referred for transvenous electrical cardioversion of AF were treated...
Sotalol is usually started in a hospital so your healthcare provider can monitor your heart rate and rhythm for the first few days to make sure the medicine is safe and working well. Do not share sotalol with other people, even if they have the same condition as you. It may harm them....
Label Stop administering sotalol and observe the patient until the QT interval returns to normal and the heart rate rises above 50 beats per minute.Label Hemodialysis may help lower plasma concentrations of sotalol as it is not bound to plasma proteins.Label Bradycardia and cardiac asystole may be...
[1]. These factors include low serum K+, slow heart rate, genetic factors (e.g., mutations affecting ion channels), other cardiac conditions, coadministered drugs that also block hERG, coadministered drugs that inhibit metabolism (e.g., terfenadine), and gender. Some patients can have LQT ...
Sinus bradycardia (heart rate less than 50 bpm) occurred in 13% of patients receiving sotalol in clinical trials, and led to discontinuation in about 3% of patients. Bradycardia itself increases the risk of Torsade de Pointes. Sinus pause, sinus arrest and sinus node dysfunction occur in less ...
This action reduces cardiac output and blood pressure, depresses sinus heart rate, and prolongs refractory period in atria and ventricles. Availability Tablets: 80 mg, 120 mg, 160 mg, 240 mg Tablets (Betapace AF): 80 mg, 120 mg, 160 mg Indications and dosages ➣ Ventricular arrhythmias ...
Formulations indicated for ventricular and atrial arrhythmias are different (Betapace versus Betapace AF); follow instructions as applicable Antacids given 2 hours or less before sotalol may reduce the bioavailability Reduce or discontinue therapy if quarterly prolongation, slow heart rate (bradycardia),...
Mild side effects associated with the use of solatol include upset stomach, heartburn, loss of appetite and arm or leg pain. Patients who experience severe reactions, such as dizziness, swelling in the face or extremities, chest tightness or confusion, should call their doctor right away. Rare...
Propranolol and sotalol as antagonists of isoproterenol-enhanced physiologic tremordoi:10.1038/clpt.1981.164Six normal subjects were studied after graded bolus injections of isoproterenol. Log dose-response curves for increases in both heart rate (mostly β1) and amplitude of physiologic tremor (β2) ...